Composition containing sugar-reducing medicine and antiplatelet medicine

Abstract

The present invention relates to a medicine composition containing hypoglycemic medicine (mainly including thiazolidione, biquanide or alpha-glycosidase inhibitor) and antiplatelet medicine (mainly including aspirin or clopidogrel). Said medicine composition contains hypoglycemic medicine or its medicinal salt with effective dose and medicinal carrier or excipient. Said invention also provides the application of said medicine composition in preparation of medicine for curing the diseases of hypertension, diabetes, inflammation and atherosclerosis, etc.

Description

Composition containing hypoglycemic drug and antiplatelet drug technical field The invention relates to a pharmaceutical composition containing hypoglycemic drugs and antiplatelet drugs, and the composition is used in the preparation and treatment of hypertension, blood lipid disorder, diabetes, abnormal blood coagulation state, inflammation, endothelial cell dysfunction, atherosclerosis or the above-mentioned Use in drugs for combination of two or more diseases. The invention belongs to the field of medicine. Background technique Atherosclerotic vascular disease (atheroscleroticcardiovasculardisease, ACVD) is the number one killer in developed countries, and it is increasingly common in developing countries. ACVD mainly includes coronary heart disease (CHD), stroke, and peripheral arterial disease. The well-recognized risk factors include hypertension, hyperlipidemia, diabetes, and endothelial dysfunction. Normal vascular endothelium plays an important role in regulat...

AI Technical Summary

Problems solved by technology

Traditional treatment methods often only intervene based on a high level of risk factors, but from some large-scale prospective studies such as the Framingham Heart Study (Framingham Heart Study), Multiple Risk Factor Intervention Trial (Multiple Risk Factor Intervention Trial, MRFTT) and prospective Cardiovascular Muster study (Prospective Cardiovascular Münsterstudy, PROCAM) can be seen, cardiovascular disease rarely depends on a single factor; the combined risk of the synergistic effect of two or more risk factors is much higher than the sum of the single risk factors At the same time, individuals with multiple risk factors, although the level of each risk factor is only slightly elevated, have a higher risk than individuals with only a very high level of risk factors

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