Cecropin and its generation bacterial strain and use

Abstract

The invention provides a CP7 strain that can produce new antibacterial polypeptides that have strong antibacterial effect to gram-positive bacteria and are small peptides with 23 amino acid residues by the determination and whose amino acid sequence is: LLLAQPTAAVRGRCQVQRYLLA A. The invention also provides the application of the new antibacterial polypeptide in the preparation of the anti gram-positive bacteria drug.

Description

A new cecropin and its production strain and application technical field The invention relates to the field of utilization of biological resources. In particular, the present invention relates to a new cecropin and its production strain and application. Background technique As we all know, since Flamin invented penicillin in 1928 and applied it to humans in the 1940s, various antibiotics produced from microbial metabolites have emerged in an endless stream, saving countless lives and making indelible contributions to human health. However, with the passage of time, people have discovered that many antibiotics have a fatal weakness, which will gradually produce drug resistance, and some will accumulate in the body, or enter the human body indirectly through the biological cycle and food chain. Antibiotics that also affect human metabolism or biosynthesis, such as chloramphenicol, have been discontinued. Therefore, people are urgently looking for substitutes or supplements...

AI Technical Summary

Problems solved by technology

However, due to the low content of antimicrobial peptides in organisms, the extraction is difficult, and the natural cost is high, which limits its practical application

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