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Chewable tablets for preventing and controlling high-altitude disease and preparation method thereof

A technology of chewable tablets and altitude sickness, which is applied in the field of chewable tablets for the prevention and treatment of altitude sickness, and achieves the effect of convenient taking, good compliance and small size

Inactive Publication Date: 2011-11-02
SICHUAN YUTUO TIBETAN MEDICINE IND CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Codonopsis pilosula, rhodiola rosea, and seabuckthorn have not been used as raw materials, nor have there been reports on the preparation of chewable tablets by combining the above three medicinal materials

Method used

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  • Chewable tablets for preventing and controlling high-altitude disease and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] The preparation of embodiment 1 chewable tablet of the present invention

[0033] a. Weigh raw materials: Codonopsis 45kg, Rhodiola rosea 15kg, fresh seabuckthorn fruit 200kg;

[0034] b. Squeeze the juice from fresh seabuckthorn fruit, filter, concentrate the filtrate to a specific gravity of 1.03-1.26, and spray dry to obtain extract powder;

[0035] c. Take Codonopsis pilosula and Rhodiola rosea, extract with water, concentrate the extract to a specific gravity of 1.03-1.26, and spray dry to obtain extract powder;

[0036] d. Mix the extract powder obtained in steps b and c, add 21kg of isomalt, and mix well; add 21kg of mannitol, mix well; add 8kg of instant starch, mix well; add CaCO 3 1kg, mix uniformly; add citric acid 8kg, mix uniformly; add stevioside 0.08kg by equal amount incremental method, mix uniformly; use 15% povidone K30 ethanol solution (ethanol concentration is 75%) appropriate amount, 40 mesh granulation, Dry at 45-80°C until the water content is ...

Embodiment 2

[0037] The preparation of embodiment 2 chewable tablet of the present invention

[0038] a. Weigh raw materials: Codonopsis 130kg, Rhodiola rosea 32.5kg, fresh seabuckthorn fruit 350kg;

[0039] b. Squeeze the juice from fresh seabuckthorn fruit, filter, concentrate the filtrate to a specific gravity of 1.03-1.26, and spray dry to obtain extract powder;

[0040] c. Take Codonopsis pilosula and Rhodiola rosea, extract with 60% ethanol, concentrate the extract to a specific gravity of 1.03 to 1.26, and spray dry to obtain extract powder;

[0041] d. Mix the extract powder obtained in steps b and c, add 23kg of isomalt, and mix well; add 20kg of lactose, mix well; add 43kg of mannitol, mix well; add 17kg of instant starch, mix well; add CaCO 3 2kg, mix well; add 17kg of citric acid, mix well; add stevioside 0.17kg by equal amount incremental method, mix well; use 15% povidone K30 ethanol solution (the ethanol concentration is 75%) in right amount, 40 order granulate, Dry at 45...

Embodiment 3

[0042] The preparation of embodiment 3 chewable tablet of the present invention

[0043] a. Weigh raw materials: Codonopsis 100kg, Rhodiola rosea 30kg, fresh seabuckthorn fruit 430kg;

[0044] b. Squeeze the juice from fresh seabuckthorn fruit, filter, concentrate the filtrate to a specific gravity of 1.03-1.26, and spray dry to obtain extract powder;

[0045] c. Take Codonopsis pilosula and Rhodiola rosea, extract with water, concentrate the extract to a specific gravity of 1.03-1.26, and spray dry to obtain extract powder;

[0046] d. Mix the extract powder obtained in steps b and c, add 20kg of isomalt, and mix well; add 25kg of xylitol, mix well; add 41kg of mannitol, mix well; add 16kg of instant starch, mix well; add CaCO 3 Add 15kg of citric acid, mix evenly; Add 0.16kg of stevioside in equal increments, mix evenly; use 15% povidone K30 ethanol solution (75% ethanol concentration) in an appropriate amount, 40 mesh granulation, Dry at 45-80°C until the water content ...

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Abstract

The invention relates to chewable tablets used for preventing and treating mountain sickness. The invention uses mountain medical substances as raw materials to prepare the chewable tablets; particularly, the invention uses common stonecrop herb, codonopsis and fructus hippophae as raw materials, and conventional excipients and adjuvant components are added to prepare, wherein, the weight proportion of the three raw materials is: 45-260 parts of codonopsis, 15-65 parts of common stonecrop herb and 200-700 parts of fructus hippophae. The invention also provides the preparation method. The chewable tablet prepared has the functions of anti-hypoxia, antiradiation, alleviating fatigue and improving immunity. If contains glucose and cane sugar, the invention is especially suitable for being taken during touring in mountain areas; if contains isomaltitol, the invention is suitable for being taken in plain areas. The invention has the advantages of small volume, convenient carrying, easy being taken (no need to be taken with boiled water), good taste and compliance, which provides novel choice for the public.

Description

technical field [0001] The invention relates to a chewable tablet for preventing and treating altitude sickness, in particular, it is a chewable tablet prepared from plateau medicinal materials as raw materials. Background technique [0002] Codonopsis pilosula, rhodiola rosea, and seabuckthorn are common plants on the plateau, and they have a long history of medicinal and edible use in my country. [0003] Codonopsis Codonopsis has the effect of invigorating the middle and replenishing qi, invigorating the spleen and promoting body fluid; it is used for weak spleen and lung, shortness of breath, palpitation, lack of appetite and loose stool, and fatigue of limbs. Salidroside and aglycone tyrosol contained in Rhodiola rosea have anti-fatigue, anti-hypoxia, anti-microwave radiation, anti-toxin, and bidirectional regulation of nervous system and metabolism, and it is also an environmental adaptation drug. Seabuckthorn fruit is rich in vitamin C and a variety of amino acids, w...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/41A61K9/20A61P43/00
Inventor 刘震东曾博程张静波
Owner SICHUAN YUTUO TIBETAN MEDICINE IND CO LTD
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