Compound compound paracetamol and zincgluconate dispersible tablet and method of preparing the same
A technology of compound aminoglucozinc and dispersible tablets, which is applied in the field of medicine, can solve the problems of slow onset of action, limitation of wide application, moderate effect, etc., achieve high bioavailability, simplify the procedure of taking, and improve the effect of cold symptoms
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Embodiment 1
[0035] Prescription: Acetaminophen 100g
[0036] Zinc Gluconate 70g
[0037] Dioxetazine Hydrochloride 1g
[0038] Banlangen extract powder 250g
[0039] Mannitol 100g
[0040] Microcrystalline Cellulose 50g
[0041] Low-substituted hydroxypropyl cellulose 50g
[0042] Crospovidone 250g
[0043] 5% PVPK30 ethanol solution 40g
[0044] Tween-80 20g
[0045] Magnesium Stearate 5g
[0046] Micronized silica gel 15g
[0047] Coffee essence 10g
[0048] Stevioside 30g
[0049] Makes 1000 pieces
[0050] Preparation method 1: Weigh the prescribed amount of acetaminophen, zinc gluconate, dioxpromazine hydrochloride, and Radix banlangen extract powder, dry them appropriately, crush them and pass through a 100-mesh sieve, add mannitol and microcrystalline cellulose , low-substituted hydroxypropyl cellulose and 150g of crospovidone are pulverized and passed through a 100-mesh sieve, adding 5% PVP...
Embodiment 2
[0072] Prescription: Acetaminophen 100g
[0073] Zinc Gluconate 70g
[0074] Dioxetazine Hydrochloride 1g
[0075] Banlangen extract powder 250g
[0076] Mannitol 100g
[0077] Cross-linked polyvinylpyrrolidone 420g
[0078] 5% PVPK30 ethanol solution 60g
[0079] Tween-60 15g
[0080] Magnesium Stearate 5g
[0081] Micronized silica gel 5g
[0082] Coffee essence 10g
[0083] A-K sugar 30g
[0084] Makes 1000 pieces
[0085] Preparation method: add Tween-60 to 5% PVPK30 ethanol solution, mix well to make adhesive for later use; weigh prescription amounts of acetaminophen, zinc gluconate, dioxpromazine hydrochloride respectively, after appropriate Dry, pulverize and pass through a 100-mesh sieve, add mannitol and 25% cross-linked polyvinylpyrrolidone in the prescribed amount, mix and pass through a 100-mesh sieve. Mix 5% PVPK30 ethanol solution and Tween-60 evenly, add 50g as a mixed binder to make a soft material, and pass through a 20-mesh sieve to make wet granul...
Embodiment 3
[0092] Prescription: Acetaminophen 100g
[0093] Zinc Gluconate 70g
[0094] Dioxetazine Hydrochloride 1g
[0095] Banlangen extract powder 250g
[0096] Sorbitol 150g
[0097] Sodium carboxymethyl starch 325g
[0098] 5% PVPK30 medicinal alcohol solution 60g
[0099] Magnesium Stearate 15g
[0100] Talc powder 15g
[0101] Orange essence 10g
[0102] Aspartame 50g
[0103] Makes 1000 pieces
[0104] Preparation method: Weigh respectively acetaminophen, zinc gluconate and dioxpromazine hydrochloride in the prescribed amount, dry properly, pulverize and pass through a 100-mesh sieve, add sorbitol and 50% of the prescribed amount of sodium carboxymethyl starch Pass through a 100-mesh sieve after mixing. Add 45g of 5% PVPK30 medicinal alcohol solution to make a soft material, and pass through a 20-mesh sieve to make wet granules A. The Radix Banlangen extract powder of...
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