Medicament composition for preventing and treating eye diseases

A technology for eye diseases and compositions, applied in drug combinations, sensory diseases, active ingredients of hydroxyl compounds, etc., can solve problems such as easy recurrence, drug resistance, and high drug toxicity, and achieve the effect of relieving visual fatigue

Inactive Publication Date: 2008-12-17
HENAN TALOPH PHARMACEUTICAL STOCK CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among the existing Chinese and Western medicine eye drops for the treatment of ophthalmic diseases, Western medicine eye drops use more antibacterial and antiviral drugs, and generally have high drug toxicity, narrow application range, long-term use, easy to produce drug resistance, easy to relapse, etc. defect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Get baicalin 30g by weight, add 2 times the amount (weight ratio) of water for injection, stir well, adjust the pH value to 8.0 with sodium hydroxide solution (content 20%), dissolve, and filter; take borneol 0.15g by weight , dissolved in 1.0ml of ethanol, slowly added to the above filtrate, then added 4.2g of sodium chloride as an osmotic pressure regulator, 1.0g of sodium hyaluronate as a thickener, stirred thoroughly, and adjusted the pH to 6.0 with a pH regulator. Finally, add water for injection to adjust the volume to 1000ml, filter through a microporous membrane, and pack separately to obtain the product.

Embodiment 2

[0018] Get baicalin 20g by weight, add 2 times the amount (weight ratio) of water for injection, stir well, adjust the pH value to 9.0 with sodium hydroxide solution (content 20%), dissolve, and filter; get borneol 0.2g by weight , dissolve with 1.5ml ethanol, slowly add to the above filtrate, stir well, adjust the pH value to 6.0 with a pH regulator, and finally add water for injection to adjust the volume to 1000ml, filter through a microporous membrane, pack in aliquots, and get ready.

Embodiment 3

[0020] Get baicalin 25g by weight, add 3 times the amount (weight ratio) of water for injection, stir well, adjust the pH value to 8.4 with sodium hydroxide solution (20%), dissolve, and filter; get borneol 0.5g by weight, Dissolve in 5ml of ethanol, slowly add to the above filtrate, then add osmotic pressure regulator glucose 4.0g, thickener sodium hyaluronate 1.5g, stir well, adjust pH value to 5.5 with PH value regulator, and finally add water for injection Adjust the volume to 1000ml, filter through a microporous membrane, and pack in aliquots.

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PUM

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Abstract

The invention provides a pharmaceutical composition for preventing and treating eye diseases, which is characterized in that the pharmaceutical composition takes baicalin and borneol as the pharmaceutical components, and uses osmo-regulator and pH regulator as the adjuvants. The weight ratios are as follows: 20-80g of baicalin, 0.1-10g of borneol, 0-4.2g of osmo-regulator and 0-2.5g of thickener. The pharmaceutical composition has the efficacies of resisting bacteria, relieving inflammation, expelling pathogenic wind, reducing fever, detoxifying and eliminating nebula, and can be used for anti-infective therapy in ophthalmology, essentially for treating conjunctivitis, keratitis, trachoma, stye and the like, and can improve tired eyesight, improve eyesight and eliminate cataract.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy, and in particular relates to a pharmaceutical composition for preventing and treating eye diseases. Background technique [0002] Common ophthalmic diseases in my country are distributed in all age groups from teenagers to middle-aged and elderly people, mainly including five major types of eye diseases: myopia, trachoma, conjunctivitis (pink eye), glaucoma and cataract. Among the existing Chinese and Western medicine eye drops for the treatment of ophthalmic diseases, Western medicine eye drops use more antibacterial and antiviral drugs, and generally have high drug toxicity, narrow application range, long-term use, easy to produce drug resistance, easy to relapse, etc. defect. However, traditional Chinese medicine eye drops have a remarkable curative effect in the clinical application of long-term treatment of ophthalmic diseases, without obvious toxic and side ef...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61K31/045A61P27/02
Inventor 邢泽田姚静
Owner HENAN TALOPH PHARMACEUTICAL STOCK CO LTD
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