Electroporation leading-in apparatus for medicament

An introduction device and electroporation technology, which is applied in the direction of drug equipment, medical science, hypodermic injection equipment, etc., can solve the problems of inability to generate electric pulses, inability to know pulse parameters, and inability to load electrode shedding detection, etc., so as to improve the utilization of drugs rate, immune-boosting effect

Inactive Publication Date: 2009-01-14
SHANGHAI TERESA BIO TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The use of electric pulses to deliver genes is a very promising technology at present. The current electric pulse devices have the following disadvantages: (1) It is impossible to generate any form of electric pulse and its pulse combination; (2) It is impossible to detect whether the load electrode has fallen off; (3) The user cannot know the pulse parameters loaded on the current load

Method used

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  • Electroporation leading-in apparatus for medicament
  • Electroporation leading-in apparatus for medicament
  • Electroporation leading-in apparatus for medicament

Examples

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Embodiment Construction

[0037] The present invention will be further described below in conjunction with the accompanying drawings and embodiments.

[0038] figure 1 The principle of a preferred embodiment of the electroporation introduction device of the drug of the present invention is shown, see figure 1 . The electroporation introduction device includes: a pulse setting module 10 , a power supply module 20 , a microcontroller 30 , a pulse display module 40 , a pulse generation module 50 , a load 60 and a shedding detection module 70 .

[0039] The pulse setting module 10 receives electric pulse parameters input by the user. For AIDS vaccines, liver disease vaccines, rabies vaccines, diabetes, etc., the electric pulse parameters should be set within the following ranges: the electric pulse frequency is 1-20Hz, the electric pulse is 1-10 per second, and the voltage is 20-400vp.

[0040] The power module 20 generates a DC signal as a driving voltage and outputs it to the pulse generation module 5...

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Abstract

The present invention discloses a medicine deliverer adopting electroperation, which improves the delivering effect of vaccinal medicines, decreases the dosage of medicines and reduces the untoward effect of medicines. In the technical scheme, the medicine deliverer adopting electroperation, which can deliver medicine into a target tissue by means of low-frequency electrical pulses, comprises a pulse-setting module, a power supply module, a microcontroller, a pulse-generating module and a load; wherein, the pulse-setting module receives an electrical pulse parameter inputted by a user; the power supply module generates a direct-current signal; the microcontroller receives the electrical pulse parameter of the pulse-setting module and outputs a control signal according to the electrical pulse parameter; the pulse-generating module receives the control signal outputted by the microcontroller and processes the direct-current signal supplied by the power supply module into an electrical pulse signal, which is then outputted; and the load receives the electrical pulse signal outputted by the pulse-generating module. The medicine deliverer adopting electroperation is applied to the field of medicinal vaccine delivery.

Description

technical field [0001] The invention relates to a drug introduction device, in particular to a device for introducing drugs into target tissues by using electroporation technology. Background technique [0002] DNA vaccine is to directly introduce the foreign gene encoding a certain antigenic protein into human or animal cells, synthesize the antigenic protein through the expression system of the host cell, and induce the host to generate an immune response to the antigenic protein, so as to achieve the purpose of preventing and treating diseases . Compared with traditional attenuated vaccines and subunit protein vaccines, DNA vaccines have the advantages of wider technical scope and more obvious cellular immune effects. Therefore, the development of therapeutic DNA vaccines is an important way for future clinical treatment. [0003] However, due to the low introduction of DNA vaccine, it objectively affects the function of the vaccine. Therefore, in order to give full pla...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M5/00A61M37/00A61D7/00
Inventor 陈丽晔
Owner SHANGHAI TERESA BIO TECH
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