Medicament composition for preventing relapse and for treating gastric ulcer

A composition and gastric ulcer technology, applied in the field of medicine, can solve the problems of slow effect and ordinary effect, and achieve the effect of short treatment period, strong antibacterial effect and strong adsorption function

Inactive Publication Date: 2009-01-21
阎玲
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine in my country is based on the theory of traditional Chinese medicine to regulate the stomach and intestines. Although its toxic and side effects are lower than those of western medicine, the effect is slow and the effect is very ordinary.

Method used

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Examples

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Comparison scheme
Effect test

preparation example Construction

[0036] The preparation method of chitosan oligosaccharides is: adding dilute lye to the raw material shrimp shells and crab shells to separate the protein and insoluble matter; solution, 110°C, 1h, deacetylated, filtered, etc., treated by enzymatic hydrolysis, dried, and crushed to a fineness of 100 meshes.

[0037]The preparation method of seaweed gel is as follows: take sea plants such as carrageenan (Chondruscrispus; C.ocellatus; Eucheuma cottonii; E.spinosum; Gigartina acicularis spp.) belonging to red algae (Rhondophyceae), extract with hot water, precipitate with alcohols, and It is obtained by drying and pulverizing to a fineness of 100 mesh.

[0038] The preparation method of dietary fiber is as follows: take readily available edible seaweed as raw material, wash and dry it, and then pulverize it. Under the conditions of pH 4-5 and temperature 48-50°C, use protease with an activity unit of 2000U / g for 1 hour. The body was treated by adding 10 times the amount of 0.1mo...

Embodiment 1

[0041] The active ingredient of the pharmaceutical composition of the present embodiment is made from the raw material of following parts by weight:

[0042] Chitooligosaccharide 85 parts

[0043] 10 parts of alginate

[0044] Dietary fiber 5 servings.

[0045] The production method of making the above-mentioned components into capsules is as follows: (1) drying the raw materials respectively and pulverizing them to a fineness above 80 mesh; (2) after fully mixing the above-mentioned powder components according to the proportion, using gamma ray irradiation, Sterilization and disinfection are carried out. The actual absorbed dose of the product is 5.0KGY. Capsules are filled, bottled and packaged according to the capsule filling process.

Embodiment 2

[0047] The active ingredient of the pharmaceutical composition of the present embodiment is made from the raw material of following parts by weight:

[0048] Chitooligosaccharide 80 parts

[0049] 10 parts of alginate

[0050] Dietary fiber 10 servings.

[0051] The production method of making the above-mentioned components into a powder is as follows: (1) drying the raw materials respectively, and pulverizing them to a fineness above 80 meshes; (2) after fully mixing the above-mentioned powder components according to the proportion, using gamma ray irradiation, Sterilization and disinfection are carried out, and the actual absorbed dose of the product is 5.0KGY, and the powder and packaging are prepared according to the powder procedure.

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Abstract

The invention discloses a medicine composition for preventing recurrence and curing gastric ulcer. The active components contain the raw materials with the following parts by weight: 10 to 85 portions of chito-oligosaccharide, 5 to 90 portions of algae colloid and 0 to 25 portions of dietary fiber. The medicine composition, with definite efficacy, naturalness and no toxicity and side effect, can form highly mucous gel similar to biological gastric mucus of human body with high antibacterial effect and viscosity in stomach body. When adverse factors reduce the secretion and synthesis of gastric mucus, the composition can timely supplement the biological gastric mucus of human body so as to ensure an important protection barrier for gastric mucosa is obtained and the composition effectively prevent recurrence and cure gastric ulcer, which is different from the conventional curing method of using antacid agent and anti-secretion agent to inhibit excessive secretion of gastric acid.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for preventing recurrence and treating gastric ulcer. Background technique [0002] Gastric ulcer is a global frequently-occurring and common disease, and it is estimated that about 10% of the population has suffered from this disease in their lifetime. Gastric ulcer manifests as hunger discomfort, fullness, belching, pantothenic acid or chronic mid-upper abdominal pain at regular intervals after meals. People's health and daily life should be highly valued. [0003] The upper surface of the human gastric organ wall is a thin layer of gastric mucosa, which consists of three layers: epithelium, lamina propria, and muscularis muscularis. Humans can eat raw food, raw meat, and even live small animals, such as lizards, because stomach acid has a strong digestive ability and can digest them; while the human stomach is also meat but cannot be...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/02A61P1/04A61K36/00A61K31/722
Inventor 阎玲
Owner 阎玲
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