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Dry powder inhalation device for the simultaneous administration of more than one medicament

一种干粉吸入、药剂的技术,应用在吸入器、药物的器械、其他医疗器械等方向,能够解决患者健康威胁、治疗效果变差、分解产物没有疗效等问题

Inactive Publication Date: 2009-04-01
ELPEN PHARMA CO INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, the presence of mixtures of active ingredients in pharmaceutical compositions creates considerable problems
Firstly there is the possibility of interactions between the active ingredients included in the mixture, which can lead to their decomposition
This result at best results in a less effective treatment due to the presence of less active ingredient in each dose, and at worst the patient may be at risk because the breakdown products are not only not curative but also May pose a threat to the patient's health
Furthermore, the presence of mixtures of active ingredients creates problems with the development of suitable pharmaceutical compositions, since each active ingredient has its own physical and chemical properties, which are not necessarily compatible with the corresponding properties of the other ingredients
Therefore, the development of a pharmaceutical composition suitable for the two components of the mixture becomes more difficult

Method used

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  • Dry powder inhalation device for the simultaneous administration of more than one medicament
  • Dry powder inhalation device for the simultaneous administration of more than one medicament
  • Dry powder inhalation device for the simultaneous administration of more than one medicament

Examples

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Embodiment Construction

[0025] figure 1 An example of a dry powder inhalation device suitable for simultaneously administering more than one pharmaceutical compound is shown, wherein the powder is packed in blisters of a single-dose blister strip, and wherein the device comprises a mouthpiece A, a blister strip support surface B and C with storage compartment.

[0026] Blister with support surface B ( figure 2) includes a protrusion 1 that acts as an attachment point, two cavities 2 and 3 that house the blister of the strip, and a guide 4 for proper alignment and secure placement of the strip. The nozzle A is movably coupled to the support surface B. As shown in FIG. In order to allow the strip to be placed in the device, the suction nozzle A is lifted from its basic position.

[0027] image 3 An example of a suction nozzle according to the invention is shown. The mouthpiece consists of three main parts: an outer part 5 which the patient places in his mouth during inhalation, and two inner par...

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PUM

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Abstract

The present invention relates to a dry powder inhalation device which is suitable for the simultaneous administration of a combination of pharmaceutical ingredients, wherein each pharmaceutical ingredient is packed in a separate blister of the same single dose blister strip. The medicaments that form the combination come into contact just before their exit from the mouthpiece of the device.

Description

technical field [0001] The present invention relates to a dry powder inhaler device suitable for the simultaneous administration of a combination of different medicaments, wherein each medicament is packed in individual blisters of a single-dose blister strip. Background technique [0002] Administration by inhalation is one of the most successful methods that can be applied in therapy for a wide variety of diseases. Initially inhaled medicaments were used to treat diseases affecting the airways; however recently the development of inhaled forms of medicaments against various other diseases such as diabetes has attracted increasing attention. [0003] Administration by inhalation is performed by using an inhalation device (inhaler). The state of the art includes a large number of such devices. Many types of inhalers include those in which the medicament is in the form of a dry powder in a reservoir and in which the patient, by using the power of his / her lungs, generates an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M15/00
CPCA61M2015/0043A61M15/0028A61M2015/0025A61M2015/0003A61M2202/064A61M15/0003A61M15/0025A61M15/0043A61M15/00
Inventor 季米特里奥斯·彭塔弗拉加斯
Owner ELPEN PHARMA CO INC
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