Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Ophiopogon root dispensing granule as well as preparation method and quality control method thereof

A technology of formula granules and Ophiopogon japonicus, which is applied in the field of traditional Chinese medicine formula granules and its preparation method and quality control, and can solve problems such as difficulties in spectrum analysis

Inactive Publication Date: 2009-07-08
BEIJING KANGRENTANG PHARMA
View PDF0 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the fact that Chinese herbal medicines, herbal pieces and Chinese patent medicines are much more complex mixture systems than western medicines, it is difficult to analyze the spectra, so that conventional infrared spectroscopy has not been able to play its due role in the quality control and management of traditional Chinese medicines for a long period of time. the role of

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Ophiopogon root dispensing granule as well as preparation method and quality control method thereof
  • Ophiopogon root dispensing granule as well as preparation method and quality control method thereof
  • Ophiopogon root dispensing granule as well as preparation method and quality control method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Embodiment 1: Ophiopogon japonicus formula granules

[0037] Take 100kg of Ophiopogon japonicus slices, add 800kg of water, extract for 2 hours, that is, the first decoction; after the first decoction, add 800kg of water to the dregs, extract for 1.5 hours, that is, the second decoction; combine the two decoctions, concentrate under reduced pressure to a relative density of 1.05- 1.10; the concentrated solution is preheated at 45°C, the inlet air temperature is 180°C, the material pump speed is 550 rpm, the outlet air temperature is 80°C, and the air delivery temperature is 45°C, and the spray-dried powder is obtained to obtain Ophiopogon japonicus spray-dried powder; Add the auxiliary material dextrin of its own weight portion 0-5% in the spray-dried powder of winter; The spray-dried powder of Ophiopogon japonicus is 5MPa in the pressure of main pinch wheel, and the pressure of side pinch wheel is 0.5MPa, and the spindle speed is 400 rpm, and the feeding voltage Dry gr...

Embodiment 2

[0038] Embodiment 2: Ophiopogon japonicus formula granules

[0039] Take 100kg of Ophiopogon japonicus decoction pieces, add 1000kg of water, extract for 2 hours, that is, the first decoction; after the first decoction, add 600kg of water to the dregs, extract for 1 hour, that is, the second decoction; combine the two decoctions, concentrate under reduced pressure to a relative density of 1.00— 1.05; the concentrated solution is preheated at 50°C, the inlet air temperature is 170°C, the material pump speed is 600 rpm, the outlet air temperature is 75°C, and the air supply temperature is 50°C, and spray-dried to obtain Ophiopogon japonicus spray-dried powder; Add 5-15% of its own weight of auxiliary material dextrin to the winter spray-dried powder; under the conditions that the main pressure wheel pressure is 6MPa, the side pressure wheel pressure is 0.4MPa, the spindle speed is 450 rpm, and the feeding voltage is 110V Dry granulation to obtain 20-60 mesh Ophiopogon japonicus ...

Embodiment 3

[0041] Embodiment 3: Ophiopogon japonicus formula granules

[0042] Take 100kg of Ophiopogon japonicus slices, add 1400kg of water, extract for 2.5 hours, that is, the first decoction; after the first decoction, add 1100kg of water to the dregs, extract for 2.5 hours, that is, the second decoction; combine the two decoctions, concentrate under reduced pressure to a relative density of 1.10- 1.15; the concentrate is preheated at 45°C, the inlet air temperature is 170°C, the material pump speed is 600 rpm, the outlet air temperature is 75°C, and the air supply temperature is 50°C, and the spray-dried powder is obtained to obtain Ophiopogon japonicus spray-dried powder; Add 15-25% of its own weight of lactose to the winter spray-dried powder; dry process under the conditions that the pressure of the main roller is 4MPa, the pressure of the side roller is 0.4MPa, the speed of the main shaft is 500 rpm, and the feeding voltage is 130V. granules, to obtain 20-60 mesh Ophiopogon japo...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a dwarf lilyturf root dispensing granule as well as a preparation method thereof and a quality control method thereof, the dispensing granule takes dwarf lilyturf root pieces as raw materials and is subjected to process flows like extraction twice with water, reduced pressure concentration, spray and drying to obtain the dwarf lilyturf root dispensing granule, the lilyturf root dispensing granule per gram is equivalent to 3-5 grams of crude drug, both the lilyturf root pieces and the dwarf lilyturf root dispensing granule use infrared fingerprint to perform an quality authentication. The inventive dwarf lilyturf root dispensing granule has integral, advanced production processes and controllable quality control criteria with strong specificity, the processes are advanced and can be realized, detection methods to which the quality criteria relates are scientific, advanced, fast and convenient with strong operability. As proved by numerous experiments, the decoction composed by the lilyturf root dispensing granule of the invention has the same ingredients as the pieces mixedly decocted liquor, the prescription granule process of bulk composition is realized and the rationality of the process of the invention is proved; furthermore, the invention applies the technology of infrared fingerprint spectra to the quality control of the traditional Chinese medicine, thus the primary problem in the macro quality control of the traditional Chinese medicine---the authenticity appraisal of the traditional Chinese medicine is instantly solved.

Description

technical field [0001] The invention relates to a traditional Chinese medicine formula granule, a preparation method and a quality control method thereof, in particular to an Ophiopogon japonicus formula granule, a preparation method and a quality control method thereof. Background technique [0002] Traditional Chinese medicine formula granules, under the guidance of the theory of traditional Chinese medicine, are made of Chinese herbal decoction pieces through various processes, and are used in clinical prescriptions of traditional Chinese medicine. Compared with traditional Chinese medicine decoction, it is convenient to take and the dosage is small , the quality is controllable, easy to store, and easy to carry; Chinese medicine formula granules are currently in the pilot production state in China, and the product technology and quality standards are not uniform. At present, traditional Chinese medicine formula granules are mostly extracted with water, or extracted with ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/8968A61K9/16A61J3/00G01N21/35G01N21/3563
Inventor 吴玢付静张翠
Owner BEIJING KANGRENTANG PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com