Spray for preventing and treating skin damnification and resisting infection

A technology for skin damage and anti-infection, applied in skin diseases, local antibacterial agents, aerosol delivery, etc., can solve the problems of high treatment cost, obvious toxic and side effects, low-level development and utilization, etc., and achieve low treatment cost, toxic and side effects Small, stable effect

Inactive Publication Date: 2009-11-25
THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, China has become the country with the largest propolis production and export volume in the world. Due to the lack of systematic and in-depth research on the medicinal value of propolis for a long time, the development of the domestic propolis market has just started in the early 1990s. Although A small amount of propolis health care products have appeared in the domestic market, but more than 90% of them are still under low-level development and utilization. Retrieval proves that no valuable, influential and high-level medicines have been developed using propolis as raw materials at home and abroad.
[0003] The existing dermatology drug market mainly supplies chemical drugs and biological agents, and there is still a lack of pure traditional Chinese medicine or natural drug preparations for skin disease treatment. Compared with traditional Chinese medicine, chemical drugs have obvious curative effects in a short period of time, but long-term use is not enough. Safe, with obvious toxic and side effects, and the drug effect is extremely unstable. After stopping the drug, it is easy to cause the disease to recur, and the treatment cost is high

Method used

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  • Spray for preventing and treating skin damnification and resisting infection
  • Spray for preventing and treating skin damnification and resisting infection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Get propolis 16g, add 95% ethanol 100ml, fully stir. Then add Tween-80, 132ml while stirring, and stir well. Then 768ml of distilled water was slowly added to obtain solution 1. Accurately weigh 50 g of monoammonium glycyrrhizinate, and dissolve it in 1000 ml of distilled water at 90°C. After dissolving, cool to 45°C, and while stirring solution 1, slowly add it into the above-mentioned monoammonium glycyrrhizinate solution to obtain solution 2. Finally, 2g of borneol was weighed and dissolved in 11ml of 95% ethanol, and slowly added to solution 2 to adjust the pH value of the solution to about 5, and the spray was obtained after bottling.

Embodiment 2

[0017] Get 100g of propolis, add 388ml of 95% ethanol, and stir well. Then add Tween-80, 377ml while stirring, and stir well. Then, 623 ml of distilled water was slowly added to obtain solution 1. Accurately weigh 40 g of monoammonium glycyrrhizinate, and dissolve it in 600 ml of distilled water at 90°C. After dissolving, cool to 45°C, and while stirring solution 1, slowly add it into the above-mentioned monoammonium glycyrrhizinate solution to obtain solution 2. Finally, 3g of borneol was weighed and dissolved in 12ml of 95% ethanol, which was slowly added to solution 2 to adjust the pH value of the solution to about 5.5, and the spray was obtained after bottling.

Embodiment 3

[0019] Get 4g of propolis, add 25ml of 95% ethanol, and stir well. Then add Tween-80, 57ml while stirring, and stir well. Then, 1413 ml of distilled water was slowly added to obtain solution 1. Accurately weigh 10 g of monoammonium glycyrrhizinate, and dissolve it in 500 ml of distilled water at 90°C. After dissolving, cool to 45°C, and while stirring solution 1, slowly add it into the above-mentioned monoammonium glycyrrhizinate solution to obtain solution 2. Finally, 1g of borneol was weighed and dissolved in 5ml of 95% ethanol, and slowly added to solution 2 to adjust the pH value of the solution to about 5, and the spray was obtained after bottling.

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Abstract

The invention discloses a spray for preventing and treating the skin damnification and resisting the infection, belonging to the Chinese medicine preparation field. The spray is prepared from the following components based on the weight percent: 0.2 to 5% of bee glue, 1 to 20 % of 95%ethanol, 3 to 20% of tween 80, 0.04 to 0.3 % of borneol, 0.5 to 8% of mono-ammonium glycyrrhizinate and the balance of distilled water. the medicament of the invention is a Chinese medicine spray for preventing and treating the skin damnification and resisting the infection. The spray has stabilizing curative effect, little toxic side effect, safe use and lower treating cost.

Description

technical field [0001] The invention relates to a pharmaceutical composition for external use, in particular to a spray for preventing and treating skin damage and anti-infection. Background technique [0002] Propolis is a safe, non-toxic, mild and effective natural antibiotic. In recent decades, a large number of documents have proved that propolis can inhibit and kill many kinds of bacteria, fungi and viruses at the same time, and is known as a precious natural broad-spectrum antibiotic substance. At present, China has become the country with the largest propolis production and export volume in the world. Due to the lack of systematic and in-depth research on the medicinal value of propolis for a long time, the development of the domestic propolis market has just started in the early 1990s. Although A small amount of propolis health care products have appeared in the domestic market, but more than 90% of them are still under low-level development and utilization. The ret...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/64A61K9/12A61K47/34A61P17/02A61P31/02A61K31/704A61K35/644A61K47/26
Inventor 蔡光明赵艳玲
Owner THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
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