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Pharmaceutical composition for treating angiocardiopathy

A composition and cardiovascular technology, applied in cardiovascular system diseases, drug combinations, pharmaceutical formulations, etc.

Active Publication Date: 2010-03-10
北京化药科创医药科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] For the application of berberine and puerarin combined in cardiovascular field, there is no relevant research

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Take 5g of berberine and 40g of puerarin, add appropriate amount of water for injection to dissolve, stir well, add a small amount of activated carbon for injection to decolorize and absorb impurities, stir for 30min, filter, adjust the filtrate to pH 6.0-7.0, sterilize, and fill in In ampoules, pack into 1000 pieces, and sterilize with moist heat to obtain the water injection needle for treating cardiovascular and cerebrovascular diseases of the present invention.

Embodiment 2

[0022] Take 10g of berberine and 40g of puerarin, add an appropriate amount of water for injection to dissolve, add 150g of mannitol, stir well to dissolve fully, add a small amount of activated carbon for injection to decolorize and absorb impurities, stir for 30min, filter through a 0.22um microporous membrane, and adjust the filtrate When the pH is 6.0-7.0, it is sterilized, filled in 10ml vials according to the dosage requirements, divided into 1000 tubes, and freeze-dried to obtain the freeze-dried powder injection for treating cardiovascular and cerebrovascular diseases of the present invention.

Embodiment 3

[0024] Take 5g of berberine and 50g of puerarin, add appropriate amount of water for injection to dissolve, stir well, add a small amount of activated carbon for injection to decolorize and absorb impurities, stir for 30min, filter, adjust the filtrate to pH 6.0-7.0, sterilize, fill in In ampoules, pack into 1000 pieces, and sterilize with moist heat to obtain the water injection needle for treating cardiovascular and cerebrovascular diseases of the present invention.

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PUM

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Abstract

The invention relates to a pharmaceutical composition for treating angiocardiopathy, which is specifically made by raw materials of pharmaceutical berberine and puerarin with a ratio of 1:1 to 1:10 byweight. The pharmaceutical composition is used for treating angiocardiopathy including blood disease, arrhythmia and hypertension and so on, and has reliable effect and easily-controlled quality.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating cardiovascular diseases, in particular to a pharmaceutical composition composed of berberine and puerarin, which belongs to the field of traditional Chinese medicine preparations. Background technique [0002] Berberine, also known as berberine, is an alkaloid extracted from plant medicinal materials such as Coptis chinensis and Cortex Phellodendri, and can also be synthesized artificially. Berberine is a spectrum antibiotic that has inhibitory effects on Gram-positive and negative bacteria. It is commonly used clinically as Treatment advocates infection, conjunctivitis, etc. Combining with other antibiotics such as cyclosporine, fluoroquinolones, and trimethoprim can enhance the antibacterial effect of other antibiotics. In recent years, more in-depth research has found that berberine also has various new uses such as lowering blood pressure, lowering blood sugar, anti-arrhythmia, and ...

Claims

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Application Information

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IPC IPC(8): A61K31/4375A61K31/352A61P9/00A61P9/06A61P9/12
Inventor 关屹闫冬
Owner 北京化药科创医药科技发展有限公司
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