Unlock instant, AI-driven research and patent intelligence for your innovation.

Novel process for preparing propylgallate directly from gallnuts

A technology for propyl gallate and gallnut, which is applied in the field of directly preparing propyl gallate from natural product gallnut, can solve the problems of long production method, high waste water treatment cost, serious environmental pollution, etc., and achieves avoiding high-concentration sewage discharge, Less impurities, good safety effect

Active Publication Date: 2013-07-17
JIURUI BIOLOGY & CHEM CO LTD
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The production method has a long process flow, large consumption of gallic acid raw materials, acid-base and activated carbon and other auxiliary materials, serious environmental pollution, and high cost of wastewater treatment

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The raw material Galla chinensis is crushed and passed through a 40-mesh sieve. Take 100g of quince powder and 1000ml of n-propanol. Stir and extract at 50°C for 4 hours. minutes, followed by vacuum filtration. Add 25 ml of sulfuric acid with a catalyst concentration of 80% to the filtrate, react at 80°C for 5 hours, cool to 20°C and filter, evaporate and concentrate the filtrate under reduced pressure, recover the evaporated solvent n-propanol; dissolve the concentrated material in 500mL hot water at 80°C , stirred, cooled to 15°C, and centrifuged to filter the crystals to obtain 56.8g of wet crystals of gallic acid propanol. The crude product was heated and dissolved in 750ml of water, decolorized with 2g of activated carbon for 30 minutes, vacuum filtered, and the filtrate was cooled to 10°C to crystallize for 5 hours. Centrifuge and filter, wash the material until the pH is 6.0-7.0, take the filter cake, and vacuum-dry (60° C.) to obtain 32.6 g of propyl gallate fin...

Embodiment 2

[0022] Raw material gallic gall, powdered, passed through a 40 mesh sieve, 100g of gall powder and 1000ml of n-propanol were taken, stirred and extracted at 50°C for 4 hours, 5g of activated carbon and 10g of refined diatomite adsorbent were added to the feed liquid for decolorization for 30 minutes, followed by vacuum filtration. Add 25 ml of catalytic sulfuric acid to the filtrate, react at 80°C for 5 hours, cool to 20°C and filter, evaporate and concentrate the filtrate under reduced pressure, and recover the evaporated solvent n-propanol; the concentrated material is dissolved in 500mL hot water at 80°C, stirred, and cooled to At 15°C, crystallization was centrifugally filtered to obtain 61.2g wet crystals of gallic acid propanol. The crude product was heated and dissolved in 750ml of water, decolorized with 2g of activated carbon for 30 minutes, vacuum filtered, and the filtrate was cooled to 10°C to crystallize for 5 hours, centrifugally filtered, and the material was was...

Embodiment 3

[0024] The raw material Galla chinensis is crushed and passed through a 40-mesh sieve. Take 100g of quince powder and 600ml of n-propanol. Stir and extract at 50°C for 4 hours. minutes, followed by vacuum filtration. Add catalyst and 25 ml of sulfuric acid to the filtrate, react at 80°C for 5 hours, cool to 20°C and filter, evaporate and concentrate the filtrate under reduced pressure, recover the evaporated solvent n-propanol; dissolve the concentrated material in 500mL hot water at 80°C, stir, and cool down To 15°C, crystallize and filter by centrifugation to obtain 51.6g wet crystals of gallic acid propanol, heat and dissolve the crude product with 450ml of water, decolorize with 2g of activated carbon for 30 minutes, vacuum filter, cool the filtrate to 10°C to crystallize for 5 hours, centrifugally filter and wash The material was taken until the pH was 6.0-7.0, and the filter cake was taken and vacuum-dried (60° C.) to obtain 30.4 g of propyl gallate finished product, wit...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a novel process for preparing propylgallate directly from gallnuts. The process comprises: taking horned galls or gallnuts as raw materials; performing extraction at room temperature through n-propanol; performing decoloration through activated carbon and refined kieselguhr adsorbent; obtaining a crude product by subjecting the obtained product and supersaturated n-propanolto chemical reaction under the catalysis of an acid catalyst; and refining and drying the crude product. The process has the advantages of adopting gallnut raw materials to react with n-propanol for preparing the propylgallate, ensuring high product yield, less impurity and good edible medicinal safety of products, reducing the consumption of acidic / alkaline activated carbon and other auxiliary materials, greatly reducing production cost, avoiding high-concentration sewage discharge caused during the preparation of gallic acid, reducing the pressure of industrial wastewater treatment and contributing to environmental management and protection.

Description

technical field [0001] The invention relates to a method for preparing propyl gallate, in particular to a method for directly preparing propyl gallate from natural product Galla galla. Background technique [0002] Galla gall is a gall formed by Galla aphids parasitizing on the compound leaves of several summer host plants such as Populus chinensis, Populus spp. Commonly used Chinese herbal medicines recorded in Pharmacopoeia. [0003] Galla is a biological organism. The main organic components are Galla tannins, with 66.6% of the angle, 72.5% of the belly, and 36.6% of the flowers. Gallic tannins are hydrolyzable tannins, which can be hydrolyzed into gallic acid and polyols under the action of acid, alkali or enzymes, from which various derivatives related to gallic acid can be prepared and become the precursors of various synthetic drugs , important food additives and other fine chemical products. [0004] Propyl gallate is a derivative of gallic acid esterification. I...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C07C69/84C07C67/08
Inventor 汤先赤陈学勇汤赫张全银云峰
Owner JIURUI BIOLOGY & CHEM CO LTD