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Internal gene electrical transduction apparatus

An electroconductive instrument and gene technology, which is applied in the direction of drug devices and other medical devices, can solve the problems of bulky electric pulse signal generator, inconvenient operation of test personnel, and soft stimulation of electric pulses. Easy to replace and carry

Inactive Publication Date: 2012-05-16
NINGBO SCIENTZ BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the electric pulse signal generator is bulky and cannot be carried by the test personnel, and it is inconvenient to operate

Method used

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  • Internal gene electrical transduction apparatus
  • Internal gene electrical transduction apparatus
  • Internal gene electrical transduction apparatus

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Experimental program
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Embodiment Construction

[0028] The present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments.

[0029] An in vivo gene electrotransduction instrument, comprising an electric pulse signal generator 1 and an electrode device 2, the signal output end of the electric pulse signal generator 1 is connected to the signal input end of the electrode device 2, and the electric pulse signal generator 1 includes a control circuit , the control circuit includes a CPU controller 3, a boost energy storage circuit 4, an electronic switch 5 and a bidirectional pulse output circuit 6, the CPU controller 3 is connected to the boost energy storage circuit 4, the CPU controller 3 is connected to the electronic switch 5, and the boost The pressure energy storage circuit 4 is connected with the bidirectional pulse output circuit 6 through the electronic switch 5 .

[0030] The CPU controller 3 includes a chip of model EM78P156 and peripheral circuits, the boos...

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Abstract

The invention discloses an internal gene electrical transduction apparatus, which comprises an electric pulse signal generator and an electrode device, wherein the signal output end of the electric pulse signal generator is connected with the signal input end of the electrode device, the electric pulse signal generator comprises a control circuit, the control circuit comprises a CPU controller, aboosting energy storage circuit, an electronic switch and a double-direction pulse output circuit, the CPU controller is connected with the boosting energy storage circuit, the CPUC controller is connected with the electronic switch, and the boosting energy storage circuit is connected with the double-direction pulse output circuit through the electronic switch. The internal gene electroporation instrument has the advantages that the CPU control is adopted, so the circuit structure is simple, the performance is stable, the carry is convenient, the instrument is suitable for being used as generesearch device in universities and colleges, scientific research institutions and animal medical stations, and the instrument can be free from utilizing the AC power, so the instrument is particularly suitable for being used in the experiment site and outdoors.

Description

technical field [0001] The invention relates to a bioengineering technical instrument, in particular to an in vivo gene electrical transduction instrument. Background technique [0002] The cell electroporation technology developed in the 1980s uses pulse electric shocks to cause reversible perforation of cells, thereby introducing foreign genes. At present, more mature foreign gene technologies are limited to in vitro cells. Another foreign gene introduction The method is to directly inject exogenous genes into living animals, and then apply electrical pulses to activate the injection site, so that the injected exogenous genes are finally introduced into the living cells of animals. This process requires the use of in vivo gene introduction equipment. The utility model patent with Chinese patent number 03255870.8 discloses the following technical features: it includes an electric pulse signal generator and an electrode clamp, and the electrode clamp includes a clamp rod and...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M37/00
Inventor 周芳
Owner NINGBO SCIENTZ BIOTECH