Periplaneta Americana pharmaceutical composition for treating ulcerative colitis and preparation method thereof

A technology for ulcerative colitis and Periplaneta americana, applied in the field of medicine, can solve the problems of no curative effect and poor effect of ulcerative colitis, and achieve the effect of improving curative effect and simple preparation method

Active Publication Date: 2010-09-15
SICHUAN GOODDOCTOR PANXI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] However, clinical verification results show that the above medicinal materials are not effective or have no effect on the treatment of ulcerative colitis.

Method used

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  • Periplaneta Americana pharmaceutical composition for treating ulcerative colitis and preparation method thereof

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preparation example Construction

[0032] The preparation method of the American cockroach pharmaceutical composition for the treatment of ulcerative colitis comprises the following steps:

[0033] 1. Preparation of Periplaneta americana extract:

[0034] a, coarse crushing: the dried Periplaneta americana is pulverized, and the Periplaneta americana coarse powder is prepared for subsequent use;

[0035] b. Soaking: add 3 to 5 times the amount of water for every 100kg of coarse powder, and soak for 0.5 to 2 hours at a temperature of 70 to 78°C to prepare a coarse powder mixture for later use; among them, the preferred solution is: add water The amount is 4 times the amount, the soaking time is 1 hour, and the soaking temperature is 74°C;

[0036] c, three extractions: the coarse powder mixed solution is extracted three times by decocting, and when the coarse powder mixed solution is extracted for the first time, the extraction time is 7 to 9 hours; After adding 2 to 4 times the amount of water of the remainin...

Embodiment 1

[0048] Carry out according to the above method, coarsely crush the dried Periplaneta americana, add 300Kg water for every 100Kg coarse powder, soak for 0.5 hours, the temperature is about 70°C, extract three times, the first time is 7 hours; add water 200Kg for the second time, extract 5 hours; add 200Kg of water for the third time, and extract for 3 hours; combine the three extracts, filter, and concentrate the filtrate to a relative density of 1.05-1.08 (70°C), add ethanol with a concentration of 93% w / w to make an alcohol-containing The volume is 40%, 70 ℃ heat preservation and stirring for 20 minutes, let stand for 10 hours, discard the upper layer of grease, filter the lower layer of liquid medicine, the filtrate recovers ethanol, concentrates under reduced pressure to a relative density of 1.15 ~ 1.18 (70 ℃), and concentrates at normal pressure to Moisture ≤ 25% ointment, promptly must contain Periplaneta americana extract, for subsequent use; Press the weight ratio of Pe...

Embodiment 2

[0050] Carry out according to the above method, coarsely crush the dried Periplaneta americana, add 300Kg water for every 100Kg coarse powder, soak for 0.5 hours, the temperature is about 70°C, extract three times, the first time is 7 hours; add water 200Kg for the second time, extract 5 hours; add 200Kg of water for the third time, and extract for 3 hours; combine the three extracts, filter, and concentrate the filtrate to a relative density of 1.05-1.08 (70°C), add ethanol with a concentration of 93% w / w to make an alcohol-containing The volume is 40%, 70 ℃ heat preservation and stirring for 20 minutes, let stand for 10 hours, discard the upper layer of grease, filter the lower layer of liquid medicine, the filtrate recovers ethanol, concentrates under reduced pressure to a relative density of 1.15 ~ 1.18 (70 ℃), and concentrates at normal pressure to Moisture ≤ 25% ointment, promptly must contain the Periplaneta americana extract, for subsequent use; Press the weight ratio o...

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Abstract

The invention discloses a periplaneta Americana pharmaceutical composition for treating ulcerative colitis, mainly comprising mixtures of effective components prepared from the following components in parts by weight: 0.8-1.2 parts of periplaneta Americana extract, 0.1-2.5 parts of coptis, 0.15-4.5 parts of scutellaria baicalensis, 0.15-6 parts of golden cypress and 0.15-15 parts of rheum officinale. The method for preparing the periplaneta Americana pharmaceutical composition for treating ulcerative colitis comprises the following steps of: preparing the periplaneta Americana extract, weighing, boiling and mixing the effective components to prepare the medicine composition. The preparation method is simple, gives full play to the periplaneta Americana extract and effectively improves the curative effect of the ulcerative colitis.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a Periplaneta americana pharmaceutical composition for treating ulcerative colitis and a preparation method thereof. Background technique [0002] According to literature records, Periplaneta americana is the largest insect in the cockroach family. It is native to South America. Periplaneta americana is a traditional Chinese medicinal material. It is used as medicine with dried and fresh adults. Its nature is salty, poisonous and pungent. , has the functions of dispelling blood stasis, eliminating stagnation, detoxification, diuresis, and detumescence; it is mainly used to treat children with malnutrition, tonsillitis, body mass, carbuncle sores, and centipede and snake bites. [0003] In recent years, with the continuous development of science and technology, after years of research, it has been found that the epidermis of Periplaneta americana contains sclera and chitin, bromi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61P1/04A61K35/64
Inventor 耿福能刘彬黄婉怡胡若瑛杜江
Owner SICHUAN GOODDOCTOR PANXI PHARMA
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