Method for extracting residual abamectin

Abstract

The invention relates to a method for extracting residual abamectin from crystallization mother liquor, which comprises the steps of removing ester impurities and further separating each component by using a C18 column or a silica gel column. The separation and extraction process is simple; the selected and used solvent is cheap, safe and environment-friendly, and meets the industrialized requirement; and the effective ingredient B1 has high yield and reaches about 90 percent.

Description

technical field [0001] The present invention relates to a method for extracting residual biologically active antibiotic components from antibiotic waste liquid, in particular to a method for separating and extracting effective component B1 and related biologically active components from the crystallization mother liquor of abamectin method. Background technique Abamectin, the English name Avermectins, is a class of sixteen-membered macrolide compounds with insecticidal, acaricidal and nematicidal activities first developed by Satoshi Omura of Kitasato University in Japan and Merck Company of the United States. Abamectin has been widely used in the prevention and control of animal parasitic diseases and crop pests since it came out in the early 1980s. Avermectin consists of 8 components: A1a, A1b, A2a, A2b, B1a, B1b, B2a, and B2b. There are mainly 4 types, namely A1a, A2a, B1a, and B2a, among which avermectin B1a has the strongest biological activity. The production proc...

AI Technical Summary

Problems solved by technology

The purpose of the present invention is to provide a method for extracting residual abamectin for the problem that the active components of the current abamectin crystallization mother liquor are difficult to extract. It uses column chromatography under appropriate temperature and pressure control to make the effective components The crystallization yield is more than 90%, which meets the needs of the industrial sector and solves the technical problems that people have been eager to solve for a long time but have not been successful.