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Method for applying a polymer coating to an internal surface of a container

An inner surface, fluoropolymer technology, used in chemical instruments and methods, preparation of detergent mixture compositions, medical containers, etc., can solve problems such as inability to wet water-based coatings and inability to ensure adhesion

Active Publication Date: 2010-12-29
PRESSPART
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the treated surface cannot be completely wetted with water-based paint
The coatings described here can also be applied to surfaces treated in this way, however, optimum adhesion and reduction of residual organic compounds cannot be ensured

Method used

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Examples

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Embodiment Construction

[0023] The present invention relates to an improved method of coating the inner surface of a container, especially a container for storing pharmaceutical preparations, to prevent the pharmaceutical preparations stored in the container from adhering or chemically reacting with the surface of the container, so that the pharmaceutical preparations can be produced in a precise manner. Measured doses are dispensed. Additionally, the present invention relates to an improved method of coating the interior surfaces of containers for storing pharmaceutical formulations that are substantially free of leachable organic compounds that can react with the pharmaceutical formulations stored in the container.

[0024] In particular, the present invention generally relates to a method of coating at least one surface of a container for storing a drug or other ingestible non-pharmaceutical product, the method comprising the steps of:

[0025] a) cleaning at least one surface of the container wit...

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Abstract

A method of cleaning and coating at least one surface of a container for storing a medicament or other ingestible non-pharmaceutical product, the method comprising the steps of using a water-based cleaning composition in conjunction with a water-based crosslinked acrylic resin containing coating material. The process makes the cleaning and coating technology consistent with present environmental regulations and workplace safety requirements, including control of emissions of volatile organic compounds (VOCs). Further, the concentration of extractible organic compounds has been reduced to the lowest practical level. The process is also applicable to other substrates where it is desired to have low-extractable organics and high adhesion of the subsequently applied coating.

Description

technical field [0001] The present invention relates to a method of cleaning and coating at least one surface of a container for holding a medicament, using a unique composition of an aqueous cleaning agent and a special aqueous coating composition, wherein the aqueous cleaning agent is used to increase surface wetting properties and The aqueous coating composition is designed to significantly reduce leachable organics and provide effective drug barrier and low sticking tendency. Background technique [0002] Medications for the treatment of respiratory and nasal conditions are usually administered orally or nasally as aerosol compositions. One widely used method of formulating such aerosol drug compositions involves preparing the drug as a suspension or solution in finely divided powder form in a liquefied gas known as a propellant (propel lant). This suspension is stored in a sealed container (or tank) that can withstand pressure to keep the propellant liquid. The formul...

Claims

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Application Information

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IPC IPC(8): A61K31/138A61K9/12
CPCA61M15/009C09D5/1668C11D11/007C11D11/0041A61K31/138A61J1/00C11D3/2068C11D3/30A61M15/0065C11D3/2006A61M2202/064C09D5/1662B65D23/02A61M2205/0222C11D2111/46C11D2111/20
Inventor 约瑟夫·H·格勒格尔汉斯-赫尔根·纽格伯尔克里斯托夫·舒尔特
Owner PRESSPART
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