Blood pressure lowering capsules and preparation process thereof

A production process and capsule technology, which is applied in capsule delivery, medical preparations containing active ingredients, cardiovascular system diseases, etc., can solve the problems of large toxic and side effects, slow disintegration of traditional Chinese medicine, etc. The effect of simple process

Active Publication Date: 2011-04-20
左志军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to overcome the defects of large toxic and side effects and slow disintegration of traditional Chinese medicines used for lowering blood pressure, and to

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] (1) Eucommia leaves 210g, hawthorn 40g, cassia seeds 40g add 12 times, 10 times of water decoction twice, each time for 1 hour, filter, and the filtrate is concentrated under reduced pressure (0.08Mpa, 65°C) to a relative density of 1.10g / cm 3 (60°C) concentrated solution, add ethanol until the alcohol concentration is 60%, let it stand for 12 hours, filter, and recover ethanol (0.07Mpa, 60°C) from the filtrate under reduced pressure until the relative density is 1.20g / cm 3 (60°C), dried under reduced pressure (0.08Mpa, 60°C) to obtain dry paste A, pulverized, and passed through an 80-mesh sieve to obtain fine powder A for future use.

[0020] (2) 36g of Huai Mi, 120g of Apocynum leaves, add 10 times the amount of water to decoct 3 times, each decoction time is 2 hours, 1 hour, 1 hour respectively, filter, and the filtrate is concentrated under reduced pressure (0.08Mpa, 80°C) to a relative density of 1.20g / cm 3 (60°C) thick paste, dried under reduced pressure (0.08M...

Embodiment 2

[0023] (1) Eucommia leaves 90g, hawthorn 50g, cassia seeds 60g add 10 times, 10 times, 8 times of water decoction 3 times, each time for 1 hour, filter, and the filtrate is concentrated under reduced pressure (0.08Mpa, 60°C) to a relative density of 1.15g / cm 3 (60°C) concentrated solution, add ethanol until the alcohol concentration is 70%, let it stand for 24 hours, filter, and recover ethanol (0.07Mpa, 60°C) from the filtrate under reduced pressure until the relative density is 1.15g / cm 3 (60°C), dried under reduced pressure (0.08Mpa, 60°C) to obtain dry paste A, pulverized, and passed through an 80-mesh sieve to obtain fine powder A for future use.

[0024] (2) 60g Sophora japonica, 180g Apocynum leaves, add 10 times the amount, 8 times the amount of water to decoct twice, each decoction time is 1 hour, filter, and the filtrate is concentrated under reduced pressure (0.08Mpa, 60°C) to relative density 1.25g / cm 3 (60°C) thick paste, dried under reduced pressure (0.08Mpa, 6...

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Abstract

The invention relates to blood pressure lowering capsules and a preparation process thereof, in particular to pagodatree flower bud-eucommia bark pulse pressure capsules and a preparation process thereof. The pagodatree flower bud-eucommia bark pulse pressure capsules consist of the following components in part by weight: 20 to 150 parts of cassia seed, 10 to 100 parts of pagodatree flower bud, 10 to 100 parts of hawthorn, 30 to 260 parts of dogbane leaf and 40 to 400 parts of eucommia bark leaf, wherein the components are prepared into particles by extracting, condensing and drying and are filled into the capsules. The blood pressure lowering capsules have the outstanding advantages of slow and stable pressure lowering effect on the treatment of hypertension, remarkable symptom improvement, small side effect, simple preparation process, small administration dose and quick absorption, are convenient to take, carry and store, are pure Chinese medicinal preparations and safe and effective pressure lowering medicaments, can be applied clinically for a long time and are particularly suitable for patient suffering from mild and moderate hypertension.

Description

technical field [0001] The invention relates to a capsule for lowering blood pressure and a production process, in particular to a Huaizhong pulse pressure capsule and a production process. Background technique [0002] Hypertension is a common cardiovascular disease in my country. It is more common in middle-aged and elderly people after the age of 40, and its incidence rate is increasing year by year. The disease is a systemic disease with arteriosclerosis as the basic lesion. The course of the disease is long and the symptoms are vague and indefinite. Its complication, cerebral apoplexy, has become one of the main causes of death and disability in my country. Therefore, the research on the treatment of hypertension has been paid attention to by people. The western medicines currently used for lowering blood pressure are mainly diuretics, β receptor blockers, calcium ion antagonists, angiotensin I-converting enzyme inhibitors, etc. These drugs have obvious toxic and side ...

Claims

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Application Information

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IPC IPC(8): A61K36/734A61K9/48A61P9/12
Inventor 李强
Owner 左志军
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