Chinese patent medicine for treating constipation and preparation method thereof
A technology for treating constipation and Chinese patent medicine, which is applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and drug combinations, etc., and can solve problems such as difficulty in excretion, poor excretion, and dry feces.
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Embodiment 1
[0022] Coptidis 70g and aloe vera 50g are mixed with ethanol and water to extract twice, each time with 1500ml of ethanol and 600ml of water for 1 hour, the filtrate is concentrated into an extract, add 250ml of water to make the extract into a suspension, and then use ethyl acetate and n-butanol were extracted twice, 250ml each time, and the extract was separated with a macroporous resin column, and 120g of NKA-9 macroporous resin was selected, with an effective column length of 60cm and a diameter of 4.5cm, eluted with n-hexane, and concentrated to Dried to become dry extract powder. Mix with 8g of red stone fat and 10g of black sesame, and then add pharmaceutical excipients to make various preparations.
Embodiment 2
[0024] Extract 50g of Coptis chinensis and 20g of aloe vera twice with ethanol and water, extract with 1000ml of ethanol and 1100ml of water for 1 hour each time, concentrate the filtrate into an extract, add 900ml of water to make the extract into a suspension, and then use ethyl acetate Extract 2 times with n-butanol, 700ml each time. The extracts are filtered and combined, concentrated to dryness to become dry extract powder. Mix with 8g red stone fat, 5g black sesame, add 5.0g medicinal starch, appropriate amount of 50% ethanol, and granulate , whole grains, dried, filled with 2# capsules.
Embodiment 3
[0026] Take 5.0g of Coptis chinensis and Aloe Vera extracts, mix them with 6g of red stone fat, 3g of black sesame seeds to make a mixture (M), 30.0g of medical starch, 30.0g of dextrin, and an appropriate amount of 50% ethanol. Stir and mix to make granules, dry at 60-70°C for 2-4 hours, and make 1000 pieces.
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