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Starch polysaccharide-iron compound preparation

A technology of starch polysaccharides and compound preparations, which is applied in the field of medicine, can solve the problems of inconvenience in taking medicine and increase the cost of medicine for patients, and achieve the effects of no hidden dangers of toxic and side effects, lower cost of medicine and less side effects

Inactive Publication Date: 2012-03-28
QINGDAO UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Taking unilateral iron or calcium supplement products is often difficult to meet the actual needs of patients. Even if various unilateral iron or calcium supplements are taken at the same time, a certain therapeutic effect can be achieved. Inconvenience, but also increase the cost of medication for patients

Method used

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  • Starch polysaccharide-iron compound preparation
  • Starch polysaccharide-iron compound preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The contents of the main drugs and auxiliary materials in the starch polysaccharide iron compound preparation are as follows:

[0031] Starch polysaccharide iron 300g

[0032] Calcium carbonate 100g

[0033] Casein phosphopeptide 1.7g

[0034] Vitamin C 20g

[0035] Starch 25g

[0036] Mannitol 300g

[0037] Acesulfame 0.75g

[0038] Magnesium stearate 2g

[0039] Peppermint flavor 1.5g

[0040] A total of 1,000 capsules were produced

[0041] The preparation method of the starch polysaccharide iron compound preparation has the following characteristics: the starch is prepared into an 11.5% starch solution, and acesulfame K is added and mixed uniformly to make a starch slurry; then calcium carbonate, casein phosphopeptide, vitamin C and Mix mannitol evenly, add starch slurry to make soft material, granulate with 16-mesh sieve, and dry at 50-60℃ to obtain dry granules, and then granulate. Magnesium stearate and mint flavor, particle size 0.1-0.45 The starch polysaccharide iron powder ...

Embodiment 2

[0043] Starch polysaccharide iron 350g

[0044] Calcium carbonate 250g

[0045] Casein phosphopeptide 17g

[0046] Vitamin C 25g

[0047] Starch 25g

[0048] Mannitol 80g

[0049] Acesulfameil 1.0g

[0050] Magnesium stearate 3g

[0051] Peppermint flavor 3.8g

[0052] A total of 1,000 capsules were produced

[0053] The preparation method of the starch polysaccharide iron compound preparation has the following characteristics: the starch is prepared into an 11.5% starch solution, and acesulfame K is added and mixed uniformly to make a starch slurry; then calcium carbonate, casein phosphopeptide, vitamin C and Mix mannitol evenly, add starch slurry to make soft material, granulate with 16-mesh sieve, and dry at 50-60℃ to obtain dry granules, and then granulate. Magnesium stearate and mint flavor, particle size 0.1-0.45 The starch polysaccharide iron powder of mm and the dry granules are mixed uniformly, and the starch polysaccharide iron compound preparation is obtained by filling the caps...

Embodiment 3

[0055] Starch polysaccharide iron 400g

[0056] Calcium carbonate 250g

[0057] Casein phosphopeptide 3.5g

[0058] Vitamin C 5g

[0059] Starch 20g

[0060] Mannitol 70g

[0061] Acesulfame 1.5g

[0062] Magnesium stearate 3g

[0063] Peppermint flavor 2.0g

[0064] A total of 1,000 capsules were produced

[0065] The preparation method of the starch polysaccharide iron compound preparation has the following characteristics: the starch is prepared into an 11.5% starch solution, and acesulfame K is added and mixed uniformly to make a starch slurry; then calcium carbonate, casein phosphopeptide, vitamin C and Mix mannitol evenly, add starch slurry to make soft material, granulate with 16-mesh sieve, and dry at 50-60℃ to obtain dry granules, then granulate, magnesium stearate and peppermint flavor, particle size 0.1~0.45 The starch polysaccharide iron powder of mm and the dry granules are mixed uniformly, and the starch polysaccharide iron compound preparation is obtained by filling the caps...

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Abstract

The invention discloses a starch polysaccharide-iron compound preparation. The starch polysaccharide-iron compound preparation is characterized in that the starch polysaccharide-iron compound preparation is prepared by combining starch polysaccharide-iron, calcium carbonate, casein phosphopeptides and vitamin C together according to a certain proportion. The starch polysaccharide-iron compound preparation has the advantages of reasonable composition and high absorption ratio of iron and calcium, has the effects of treating the iron-deficiency anemia and supplementing calcium, and is particularly applicable to pregnant women, children, old people and other crowds tending to suffer from iron-deficiency anemia and calcium deficiency.

Description

1. Technical Field [0001] The invention relates to a starch polysaccharide iron compound preparation, which belongs to the technical field of medicine. 2. Background technology [0002] The main way to treat iron deficiency anemia is to supplement the body with sufficient iron. Existing drugs for the treatment of iron deficiency anemia are mainly divalent iron iron supplements, such as ferrous sulfate, ferrous lactate, ferrous gluconate, ferrous citrate, etc., which have great gastrointestinal side effects and can cause nausea, Adverse reactions such as abdominal pain and diarrhea make it difficult for many patients to accept. Although porphyrin iron and ferric ammonium citrate have no side effects on the stomach, the production cost of porphyrin iron is high, and the price exceeds the affordability of many patients. In addition, ferric ammonium citrate has a rusty taste and has a bad taste. It is prone to disgust when taken, and is not easy to be accepted by the general populat...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/715A61K33/10A61K38/02A61K31/375A61P3/02A61P7/06
Inventor 张媛媛刘均洪
Owner QINGDAO UNIV OF SCI & TECH
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