Seabuckthorn leaf extract preparation and preparation method thereof

A technology of sea buckthorn leaves and extracts, applied in the directions of anti-inflammatory agents, anti-toxic agents, drug combinations, etc., can solve the problems of high cost, low flavonoid content, large dosage, etc., and achieves low price, high flavonoid content, and biological Resourceful Effects

Inactive Publication Date: 2012-10-03
TIANJIN TAIYANG PHARMA
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The seabuckthorn extracts used in current products are basically extracted from seabuckthorn fruits. The flavonoid content of the preliminary extracted products is generally not high, and the amount of use is relatively large, and some are further refined to increase the effective content of seabuckthorn extracts. Ingredient content, high cost

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Seabuckthorn leaf extract preparation and preparation method thereof
  • Seabuckthorn leaf extract preparation and preparation method thereof
  • Seabuckthorn leaf extract preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1: the preparation of seabuckthorn leaf extract

[0023] Weigh 100g of dried seabuckthorn leaves, crush them to below 20 meshes, use 80% ethanol aqueous solution 800ml, 600ml, 400ml to reflux extract 3 times at 70°C for 3 hours each time, filter and combine the extracts, and recover ethanol under reduced pressure , add water to the concentrated extract to make up to 400ml, let stand at room temperature for 12 hours, filter, add water to the filtrate to make up to 400ml. Measure 100ml of FL-2 adsorption resin, put it into the adsorption column by wet method, soak it with 90% ethanol for 12 hours, and then gradually transition to the water phase, 400ml of seabuckthorn leaf extract passes through the adsorption column at a flow rate of 1BV / h, and then wash it with 100ml of water , and then eluted with 70% aqueous ethanol at a flow rate of 0.5BV / h, collected the eluent, concentrated to dryness under reduced pressure to obtain a yellow-brown extract powder, and th...

Embodiment 2

[0024] Embodiment 2: Preparation of seabuckthorn leaf extract tablet

[0025] Get embodiment 1 Seabuckthorn leaf extract 20g, add starch 40g, microcrystalline cellulose 40g, magnesium stearate 0.1g, compress after mixing, obtain Seabuckthorn leaf extract tablet, be 0.5g with gained tablet quality as For example, each tablet should contain no less than 40mg of total flavonoids from seabuckthorn.

Embodiment 3

[0026] Example 3: Preparation of Seabuckthorn Leaf Extract Capsules

[0027] Take 40g of seabuckthorn leaf extract, add 60g of starch, mix well, granulate, dry, and pack into seabuckthorn leaf extract capsules. Taking the obtained capsule mass as 0.25g as an example, the total flavonoids of seabuckthorn contained in each capsule should not be less than 40 mg.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a seabuckthorn leaf extract preparation and a preparation method thereof. The preparation comprises the following components in percent by weight: 1-50 percent of seabuckthorn leaf extract and 50-99 percent of auxiliary materials. The preparation has the advantages of high content of effective components, less consumption, no toxic and side effects, easiness of preparation, and the like, and can be clinically used for preventing, treating and improving symptoms of relevant heart cerebrovascular diseases. The preparation can be prepared into a pill preparation, a capsule preparation, an injection preparation, granule preparation, an oral solution or other multiple preparations accepted by clinical application according to corresponding processes.

Description

technical field [0001] The invention relates to a seabuckthorn leaf extract preparation and a preparation method thereof, belonging to the technical field of traditional Chinese medicine preparations. Background technique [0002] Seabuckthorn (Hippophae rhamnoides L.) is a plant of the family Echinacea. It is distributed in North China, Northwest China, and Southwest my country. Seabuckthorn is rich in a variety of biologically active substances, and more than 190 biochemical components have been discovered so far. The roots, stems, leaves, flowers and fruits of seabuckthorn, especially the fruit of seabuckthorn contain rich nutrients and biologically active substances. Among them, the fruit of seabuckthorn contains a variety of flavonoids, such as isorhamnetin, rutin, milk vetch Glycosides, quercetin and kaempferol are low glycosides of aglycones, and also contain multivitamins, dehydroascorbic acid, folic acid, carotene, etc.; seeds contain oil, including palmitic acid, ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/185A61P1/00A61P7/00A61P9/10A61P17/16A61P29/00A61P35/00A61P37/04A61P37/08A61P39/06A61K127/00
Inventor 欧来良王为超
Owner TIANJIN TAIYANG PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap