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Compound florfenicol preparation for aquatic products and preparation method and application thereof

A technology of florfenicol and florfenicol, which is applied in the field of compound florfenicol preparations for aquatic products and its preparation, can solve problems such as inapplicability and complex components, and achieve increased targeting effect, good curative effect, and cost reduction Effect

Active Publication Date: 2012-06-27
清远海贝生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The purpose of the present invention is to provide a kind of compound florfenicol preparation for aquatic products according to existing florfenicol preparations that are not suitable for aquatic animals or have complex components. The composition of the preparation is simple, easy to prepare, and reduces cost of production

Method used

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  • Compound florfenicol preparation for aquatic products and preparation method and application thereof
  • Compound florfenicol preparation for aquatic products and preparation method and application thereof
  • Compound florfenicol preparation for aquatic products and preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0032] (1) Separately pulverize the dried florfenicol, neomycin sulfate, and glucose pure powder with an ultrafine pulverizer until the particle size reaches 10 μm, and set aside;

[0033] (2) Weigh 5 kg of crushed florfenicol and 94 kg of pure glucose powder and mix them fully in a mixer;

[0034] (3) Add 1 kg of pulverized neomycin sulfate pure powder into the mixture of the above-mentioned florfenicol and glucose, fully mix with the mixer, discharge, and sieve to obtain the compound florfenicol of the present invention Test superfine powder.

Embodiment 2

[0036] (1) Separately pulverize the dried florfenicol, neomycin sulfate, and pure glucose powder with an ultrafine pulverizer until the particle size reaches 20 μm, and set aside;

[0037] (2) Weigh 10kg of crushed florfenicol and 82kg of pure glucose powder and mix them fully in a mixer;

[0038] (3) Add 8 kg of pulverized neomycin sulfate pure powder into the mixture of the above-mentioned florfenicol and glucose, fully mix with the mixer, discharge, and sieve to obtain the compound florfenicol of the present invention Test superfine powder.

Embodiment 3

[0040] (1) Separately pulverize the dried florfenicol, neomycin sulfate, and pure glucose powders with a superfine pulverizer until the particle size reaches 30 μm, and set aside;

[0041] (2) Weigh 20kg of crushed florfenicol and 60kg of pure glucose powder and mix them fully in a mixer;

[0042] (3) Add 20 kg of pulverized neomycin sulfate pure powder into the mixture of the above-mentioned florfenicol and glucose, fully mix with the mixer, discharge, and sieve to obtain the compound florfenicol of the present invention Test superfine powder.

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Abstract

The invention discloses a compound florfenicol preparation for aquatic products and a preparation method and application thereof. The compound florfenicol preparation for the aquatic products consists of the following components in percentage by mass: 5 to 20 percent of florfenicol, 1 to 25 percent of neomycin sulfate and the balance of glucose. The florfenicol and the neomycin sulfate are combined, so that the antibacterial effect of the compound florfenicol preparation for the aquatic products can be improved, the prevention and treatment effects of the compound florfenicol preparation on the bacterial diseases of the aquatic products are effectively improved, and medicine consumption and cost are reduced; and the preparation method of the compound florfenicol preparation for the aquatic products is simple and practicable and greatly improves bioavailability, and the preparation has high solubility.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to a compound florfenicol preparation for aquatic products and its preparation method and application. Background technique [0002] In recent years, with the improvement of people's living standards, people's demand for aquatic products is increasing. However, judging from the current development status of the aquaculture industry, current aquatic bacterial diseases, such as the third disease of grass carp, are still a major problem in the aquaculture industry, bringing great losses to the aquaculture industry. [0003] At present, florfenicol is widely used in aquaculture, but the problem of drug resistance is gradually becoming prominent. Sometimes florfenicol is used alone to treat certain aquatic diseases, but the effect is not obvious, and the raw material price of florfenicol is relatively expensive. Used alone, the cost is higher. Therefore urgently need to study a kind ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7036A61K31/165A61K9/14A61P31/04
Inventor 刘晓莎
Owner 清远海贝生物技术有限公司
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