Matrix addition system for mass spectrum analysis

A mass spectrometry and matrix technology, which is applied in the analysis of materials, material analysis by electromagnetic means, and measurement devices, etc., can solve the problems of online matrix addition, inability to provide samples for time-of-flight mass spectrometers, and inability to meet biological particle detection requirements, etc.

Inactive Publication Date: 2011-07-13
北京汇丰隆经济技术开发有限公司
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  • Abstract
  • Description
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Problems solved by technology

[0006] However, the existing technology cannot provide online matrix addition for the sample to be tested by the time-of-flight mass spectrometer, and cannot meet the detection requirements for biological particles in bioaerosol samples

Method used

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  • Matrix addition system for mass spectrum analysis
  • Matrix addition system for mass spectrum analysis
  • Matrix addition system for mass spectrum analysis

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Embodiment Construction

[0028] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0029] figure 1 It is a schematic diagram of a matrix addition system for mass spectrometry according to an embodiment of the present invention. Such as figure 1 As shown, it includes: heating pool 1, heat saturation pipe 2, condensation pipe 3 and peripheral control module 7, wherein

[0030] The heating pool 1 is used to hold the matrix solution. The first heating belt 4 is fixed outside the heating pool 1. The matrix is ​​heated in the heating pool 1 and ...

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Abstract

The invention discloses a matrix addition system for mass spectrum analysis, comprising a heating bath, a thermal saturated pipe, a condenser pipe and a peripheral control module, wherein the heating bath is used for containing a matrix solution; a first heating band is fixed outside the heating bath; the thermal saturated pipe is connected with the heating bath; a second heating band is fixed outside the thermal saturated pipe and used for providing appropriate temperature for a mixed gas of aerosol particles and a matrix so that the aerosol particles and the matrix are better bonded together; the condenser pipe is connected with the thermal saturated pipe; a refrigeration sheet is fixed outside the condenser pipe and used for condensing a gas exhausted from the thermal saturated pipe to enable the vaporous matrix, which is not attached to the aerosol particles, to be liquefied and reflow to the heating bath so as to obtain the aerosol particles attached with the matrix on an outlet of the condenser pipe; and the peripheral control module is respectively connected with the first heating band, the second heating band and the refrigeration sheet and used for regulating and displaying the set temperature and the current temperature of the heating bath, the thermal saturated pipe and the condenser pipe.

Description

technical field [0001] The invention relates to a matrix addition system for mass spectrometry analysis, in particular to a system for automatically adding matrix on-line to bioaerosol samples that meet the requirements of biological particle detection. Background technique [0002] Mass spectrometry is an analytical technique that analyzes by measuring the mass-to-charge ratio of the measured sample ions. The sample to be analyzed must first be ionized, and then use the difference in motion behavior of different ions in the electric field or magnetic field to separate the ions according to the mass-to-charge ratio (m / z) to obtain a mass spectrum. According to the mass spectrum of the sample and related information, it can be Get the qualitative and quantitative analysis results of the samples. [0003] After the 1980s, some new mass spectrometry technologies appeared, such as matrix-assisted laser desorption technology and time-of-flight mass analysis technology, and the s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/62
Inventor 刘毅刘强刘航陈艳学李晓静
Owner 北京汇丰隆经济技术开发有限公司
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