Tooth whitening complex with temperature sensitive magnetic targets and preparation and operation method thereof

A compound and magnetic targeting technology, which is applied in medical preparations of non-active ingredients, active ingredients of peroxide compounds, dentistry, etc., can solve the problems of clinical application limitations, affecting bleaching effect, bleaching agent leakage, etc., and achieve the goal of manufacturing Low cost, reduced tooth sensitivity, and easy operation

Inactive Publication Date: 2011-08-31
SUN YAT SEN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when a single anterior tooth is discolored, a specific part of the tooth surface is deeply stained (brown plaque of fluorosis tooth, pigmented band of tetracycline tooth, etc.) big limit
Also, when unnecessary bleach come

Method used

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  • Tooth whitening complex with temperature sensitive magnetic targets and preparation and operation method thereof
  • Tooth whitening complex with temperature sensitive magnetic targets and preparation and operation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0029] The method for preparing a tooth whitening compound with temperature-sensitive magnetic targeting provided by the embodiment of the present invention comprises the steps of:

[0030] 101. Preparation of oleic acid modified Fe3 o 4 Nano magnetic particles;

[0031] 102. With the Fe 3 o 4 Composite A is prepared by using nano-magnetic particles as the core and covering N-isopropylacrylamide with miniemulsion polymerization;

[0032] 103. Mix and stir the compound A and carbamide peroxide for 2-4 hours at room temperature, then centrifuge, discard the supernatant to obtain the temperature-sensitive magnetically targeted tooth whitening compound.

[0033] Specifically, step 101 includes: taking FeCl 2 and FeC1 3 Dissolve at least one of the substances in deionized water, for example, take 150-200g FeCl 2 and FeC1 3 Add the mixture to 1L of deionized water and stir evenly. After heating to 60-70°C, add 30mL of ammonia water and 20mL of oleic acid, then keep stirring a...

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Abstract

The invention discloses a tooth whitening complex with temperature sensitive magnetic targets and a preparation method and an operation method thereof. The tooth whitening complex which can perform targeted positioning and has temperature sensitivity comprises a tooth cleaning component of carbamide peroxide with high oxidability and functional components such as ferroferric oxide nanoparticles and N-isopropylamide, and a carbamide peroxide complex with temperature sensitive magnetic targets is formed through chemical preparation. The complex has the characteristics of low manufacturing cost, convenience of operation and high positioning accuracy, and is easy to store, can realize the targeted and controllable release of bleaching components, can solve the problem of the leakage of bleaching agents, further improves the quality of tooth whitening, and lowers side effects of tooth sensitivity, gum inflammation and the like generated when unnecessary bleaching materials are contacted with gums.

Description

technical field [0001] The invention relates to a preparation for whitening human teeth, in particular to a tooth-cleaning compound with positioning treatment function and temperature-controlled release. Background technique [0002] Discolored teeth, defects on vital and dead pulp teeth have seriously affected the appearance of teeth. The aesthetics of teeth directly affect people's appearance and communication in daily life. People are eager to restore the natural color of teeth. Therefore, tooth bleaching has become one of the important treatment items in oral clinic. [0003] Tooth bleaching technology is the most common cosmetic treatment. It is the simplest, least damaging, and most economical way to whiten teeth. The basic process is an oxidation reaction. The bleaching agent goes into the discolored enamel and dentin to release bleaching. substance. The effect of bleaching depends on the reason for the staining, the location of the staining, the depth, the length o...

Claims

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Application Information

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IPC IPC(8): A61K8/42A61K8/38A61K8/19A61K31/327A61K47/02A61K47/16C08F220/54C08F2/44C08F2/22C08K9/04C08K3/22A61Q11/00A61P1/02
Inventor 许跃蔡斌凌均棨项露赛吴斯媛
Owner SUN YAT SEN UNIV
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