55results about "Peroxy compound active ingredients" patented technology

An animal watering system is disclosed. The animal watering system comprises an activated water source and an animal watering station configured to receive activated water from the activated water source. The activated water source comprises a unipolar electrolytic cell configured to produce activated water containing a desired amount of hydrogen peroxide. A methane conversion system comprising an activated water source and a mixer for contacting activated water from the activated water source with a gas containing methane and with a source of Fe2+ ions is also disclosed.

The invention relates to a pharmaceutical composition, which is prepared from adapalene, benzoyl peroxide, a traditional Chinese medicine extract, an acrylamide and acryloyl dimethyl sodium taurate copolymer, a mixture of isohexadecane and polysorbate 80, docusate sodium, EDTA (Ethylene Diamine Tetraacetic Acid) disodium, glycerol, poloxamer 124, propylene glycol and water, the traditional Chinese medicine extract comprises moutan bark, salvia miltiorrhiza, radix rehmanniae recen, radix sophorae flavescentis, coptis chinensis, rheum officinale, scutellaria baicalensis, menthol and borneol. According to the pharmaceutical composition disclosed by the invention, the synergistic antibacterial and anti-keratosis curative effects of adapalene and benzoyl peroxide can be maintained, and meanwhile, the occurrence rate of local skin dryness, erythema, desquamation, burning heat sensation and contact dermatitis can be remarkably reduced.

COACERVAT CLEANSING COMPOSITION WITH ACNE TREATMENT ACTIVE The disclosure relates to compositions comprising (a) at least one amphoteric surfactant, (b) at least one glycolipid, (c) at least one cationic polymer at a concentration of approximately 0.05% to approximately 2%; (d) at least one acne treatment active, and (e) at least one cosmetically acceptable solvent, in which the cleansing system is substantially free of phenoxyethanol, and in which the pH of the composition is between approximately 4 and approximately 8, and in which the weight ratio of a to b is approximately 0.4 to approximately 4, and in which the combined concentration of a and b is approximately 10% to approximately 20% of the total weight of the composition. The compositions may be used as rinse-off compositions to cleanse the skin and deposit acne treatment actives. Figure for the abstract: none

The invention discloses a method for preparing benzoyl peroxide gel and application, and belongs to the technical field of medicine preparation. The preparation method comprises the following steps: preparing a ternary eutectic solvent by taking choline chloride, glycerol and benzoic acid as raw materials, mixing benzoyl peroxide with the ternary eutectic solvent to obtain a benzoyl peroxide system, and mixing the benzoyl peroxide system with a gel system on the basis to prepare the benzoyl peroxide gel with relatively high stability, storage stability and antibacterial activity.

The present disclosure relates to compositions and methods useful for dietary augmentation to provide therapeutic intervention for the treatment and management of acne-prone skin. According to one embodiment of the present disclosure, there is provided an orally administrable composition containing a therapeutically effective amount of: (a) pantothenic acid; (b) folic acid; (c) myo-inositol; (d) methylsulfonylmethane (MSM); (e) holy basil extract; (f) optionally, turmeric root extract; (g) barberry root extract; (h) L-theanine; and (i) milk thistle extract.

The invention discloses a pharmaceutical composition. The pharmaceutical composition comprises a medicine granulated substance containing 4-((L-valyl) oxy) butyric acid and an excipient granulated substance. When the pharmaceutical composition is combined and mixed with water, the excipient particles rapidly dissolve to form a viscous solution in which the pharmaceutical granules are suspended. The pharmaceutical granulate provides a palatable oral pharmaceutical composition.

The present application relates to regimens, methods of treatment, and compositions for treating acne in a subject suffering from acne.

Provided is a benzoyl peroxide-containing composition that has smaller change in viscosity over time and can be easily removed from the skin. This skin composition comprises: (A) benzoyl peroxide; (B) an acrylamide-(sodium acryloyldimethyltaurate) copolymer; (C) a surfactant comprising at least one selected from the group consisting of (c1) a combination of sodium lauroyl sarcosinate and at least one anionic surfactant and / or nonionic surfactant, (c2) at least one anionic surfactant selected from the group consisting of sodium lauryl sulfate, polyoxyethylene alkyl ether phosphates, polyoxyethylene alkyl ether sulfates, and sodium lauroyl glutamate, and (c3) a combination of sodium oleate and at least one anionic surfactant and / or nonionic surfactant; and (D) at least one water-based solvent selected from among water and a water-soluble solvent. The skin composition is used by being applied to an affected area of the skin, left to stand for a predetermined time, and subsequently removed from the affected area.

The present invention relates to a new multifunctional debridement and / or antifouling composition comprising H2O2 at a final concentration of between 0.1 - 5%v / v, and a composite hydrogel formulation comprising pluronic acid at a concentration of 10-40%w / v, wherein the composition is in liquid form at room temperature. The composition disclosed herein is antimicrobial and / or anti-inflammatory and is particular useful in periimplantitis treatment and implant health maintenance, in periodontitis and periodontal health and in wound care and chronic ulcer care.

The present application is directed to stabilized core-shell microcapsules comprising a core of benzoyl peroxide (BPO) or all trans retinoic acid (ATRA) and a metal-oxide shell; and to pharmaceutical compositions and methods of use thereof.

Provided are a peroxide-containing liposome, a preparation method therefor, and use thereof. The peroxide-containing liposome is a spherical vesicle having a double-layer membrane structure and formed by lipid molecules containing one or more peroxy groups, and the lipid molecules contain carbon-carbon double bonds. The peroxide-containing liposome can be obtained by mixing peroxide-containing lipid molecules with an aqueous system, wherein the peroxide-containing lipid molecules are obtained by reacting unsaturated lipid molecules containing -CH=CH- and / or -C≡C- with an additive in the presence of oxygen and a solvent, and the additive is selected from one or more of lipoxygenase, an oxidation catalyst, and an oxidizing agent. By means of in-vitro experiments in cells and in-vivo experiments in animals, it is found that the peroxide-containing liposome can kill tumor cells and can be used as a sensitizing agent in combination with other tumor treatment methods to effectively improve the therapeutic effect on tumors, thus having good application prospects in resisting tumors.

Compositions and methods are provided for using DispersinB® and a second antimicrobial which does not comprise a bacteriophage or transglutaminase enzyme as a topical anti-acne treatment. The second antimicrobial may be selected from the group consisting of organic peroxide, benzoyl peroxide, tetracyclines such as minocycline and doxycycline, macrolides such as erythromycin and azithromycin, and clindamycin.

Described herein are compositions and methods for the treatment of meibomian gland dysfunction. Said compositions and methods comprise keratolytic agents, such as salicylic acid, selenium disulfide, or the like. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from meibomian gland dysfunction.

A hydrogel-based biological delivery vehicle used to effectively deliver drug and biological material to tissue or organ sites. More specifically, a hydrogel binding matrix having a biopolymer backbone containing carboxyl groups. Tyramine may be substituted for at least a portion of the carboxyl groups, so that, when hydrogen peroxide is added, it causes creation of covalent bonds between tyramine molecules and cross-links the hydrogel binding matrix, thereby enabling the hydrogel binding matrix to transition from liquid to gel state. The hydrogel binding matrix, in its liquid form, is capable of encapsulating drug reservoirs to create a homogenous liquid with evenly distributed particles containing drugs or target molecules. As the hydrogel binding matrix solidifies into a gel state, the newly created cross-links do not disrupt or react with the drugs or target molecules contained within the drug reservoirs. This hydrogel-based biological delivery vehicle can be used in several medical applications.

Various embodiments disclosed relate to a sporicidal solution. The sporicidal solution includes less than about 7 wt% acetic acid, propionic acid, or a mixture thereof. The solution further includes about 0.22 wt% to about 10 wt% hydrogen peroxide. The solution further includes about 300 ppm to about 2000 ppm peracetic acid, perpropionic acid or both. The solution further includes about 0.0098 wt% to about 1.2 wt% stabilizer. The solution further optionally includes about 10 wt% to about 80 wt% isopropyl alcohol, less than or equal to 5 wt% formic acid, and / or 0.05 wt% to about 0.5 wt% surfactant.

A hydrogel-based biological delivery vehicle used to effectively deliver drug and biological material to tissue or organ sites. More specifically, a hydrogel binding matrix having a biopolymer backbone containing carboxyl groups. Tyramine may be substituted for at least a portion of the carboxyl groups, so that, when hydrogen peroxide is added, it causes creation of covalent bonds between tyramine molecules and cross-links the hydrogel binding matrix, thereby enabling the hydrogel binding matrix to transition from liquid to gel state. The hydrogel binding matrix, in its liquid form, is capable of encapsulating drug reservoirs to create a homogenous liquid with evenly distributed particles containing drugs or target molecules. As the hydrogel binding matrix solidifies into a gel state, the newly created cross-links do not disrupt or react with the drugs or target molecules contained within the drug reservoirs. This hydrogel-based biological delivery vehicle can be used in several medical applications.

The present invention provides a tretinoin and benzoyl peroxide composition, its preparation method and use, which comprises component (i) benzoyl peroxide; component (ii) tretinoin; and (iii) a lipid material. The composition has excellent stability, and the preparation process is simple and easy to scale up production.

The invention discloses a household sterilization disinfectant preparation method, and belongs to the technical field of sterilization disinfectant preparation, and the household sterilization disinfectant preparation method comprises the following steps: S1, adding a peroxide compound into deionized water, stirring at normal temperature until the peroxide compound is completely dissolved, and preparing a mother solution with the concentration of 10-15% for later use; s2, mixing the quaternary ammonium salt compound with the antibacterial agent, adding a small amount of water, uniformly stirring, heating to 40 DEG C, and continuously stirring for 30 minutes. According to the disinfectant disclosed by the invention, the peroxide compound and the quaternary ammonium salt compound are used as main components, the disinfectant can effectively kill various bacteria and viruses and provide strong degerming ability, the components act together to ensure a wide antibacterial spectrum, the humectant and the emollient are added into the disinfectant, and the disinfectant has a good antibacterial effect. The moisture of the skin of a user can be kept, dryness and irritation are reduced, and meanwhile, the product is more suitable for being used in daily families, especially families with children or old people.

The present invention relates to a novel multifunctional wiping and / or antifouling composition comprising a composite hydrogel formulation containing HO at a final concentration of 0.1-5% v / v and pluronic acid at a concentration of 10-40% w / v, wherein the composition is in liquid form at room temperature. The compositions disclosed herein are antibacterial and / or anti-inflammatory and are particularly useful in peri-implantitis treatment and implant health maintenance, periodontitis and periodontal health, and wound care and chronic ulcer care.

The disclosure provides a topical gel formulation comprising 1-1.5 wt. % clindamycin phosphate, 2.5-3.5 wt. % benzoyl peroxide, and 0.1-0.2 wt. % adapalene, in combination with a gelling agent, a polyhydric alcohol, and water, useful in treating inflammatory skin conditions, including acne, together with methods of making and using the same.

Disclosed is a method for providing a topical formulation base. The method includes providing water, salt, and ozonated sea buckthorn oil, and combining the water, salt, and ozonated sea buckthorn oil. Also disclosed are methods for providing a topical formulation, topical formulation base compositions, topical formulation compositions, non-therapeutic methods of using said compositions, and compositions for use in therapy.

The invention relates to a personal care composition, more particularly to a composition for application to a topical surface that prevents or reduces inflammation. The composition could be delivered in the form of a skin, scalp, hair or oral care product, more particularly a skin care product. The benefit is delivered via a combination of a polyunsaturated fatty acid (PUFA) or ester thereof selected from docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), DHA-ethyl ester, EPA- ethyl ester, DHA-triglyceride, EPA-triglyceride, dihomogamma-Linolenic Acid (DGLA), DGLA-ethyl ester, DGLA-triglyceride or combinations thereof and a 4-substituted resorcinol compound, wherein the mole ratio of the PUFA or ester thereof to the 4- substituted resorcinol compound is 5:1 to 1:5.

An antimicrobial composition comprising glycerol and dihydroxyacetone is disclosed. Also, a method of making the antimicrobial composition comprising mixing a reagent comprising glycerol and an oxidant, optionally with a catalyst, is disclosed. The composition can be included in products such as a wound dressing, a food product, a cosmetic product, and a cleaning product. The compositions can be used in the prevention or treatment of a skin condition and in therapy.

A hydrogel-based biological delivery vehicle used to effectively deliver drug and biological material to tissue or organ sites. More specifically, a hydrogel binding matrix having a biopolymer backbone containing carboxyl groups. Tyramine may be substituted for at least a portion of the carboxyl groups, so that, when hydrogen peroxide is added, it causes creation of covalent bonds between tyramine molecules and cross-links the hydrogel binding matrix, thereby enabling the hydrogel binding matrix to transition from liquid to gel state. The hydrogel binding matrix, in its liquid form, is capable of encapsulating drug reservoirs to create a homogenous liquid with evenly distributed particles containing drugs or target molecules. As the hydrogel binding matrix solidifies into a gel state, the newly created cross-links do not disrupt or react with the drugs or target molecules contained within the drug reservoirs. This hydrogel-based biological delivery vehicle can be used in several medical applications.

The invention discloses application of benzoyl peroxide in preparation of a pyroptosis inducer or an antitumor drug, and relates to the technical field of biological medicines. Experiments show that BPO can effectively induce pyroptosis of soft osteosarcoma cells, the cell proliferation activity is obviously inhibited, and in-vivo experiments prove that BPO can still play an excellent anti-tumor effect in vivo by inducing pyroptosis. In addition, the invention also explores the pyroptosis induction mechanism of BPO, and finds that BPO plays a pyroptosis induction role mainly through targeting GSDMC. The research result of the invention not only widens the variety selection of the pyroptosis inducer, but also provides a new effective treatment choice for patients with soft osteosarcoma.

A method of treating acne, of treating UV or radiation induced injury, of reducing the appearance of scars, and / or of treating mucositis, including topically applying a composition including CAPE to a human or other mammal in need thereof, in a therapeutically effective amount and / or from about 1% to about 50% CAPE by weight.

The invention discloses adapalene benzoyl peroxide gel. The adapalene benzoyl peroxide gel is prepared from adapalene, benzoyl peroxide, 3%-7% of diethylene glycol monoethyl ether, 0.1%-0.3% of caprylic / capric polyethylene glycol glyceride and other pharmaceutically acceptable auxiliary materials. Through synergistic combination of the specific solvent and the surfactant, the problem that benzoyl peroxide is difficult to uniformly disperse only by conventional stirring in the prior art is successfully solved. According to the preparation method, the gel which is uniform in medicine dispersion, fine and smooth in texture and free of gravel feeling can be obtained only through conventional stirring, and complex processes such as high shearing, ultrasonic or spray drying and the like with safety risks do not need to be relied on. The process is simple, the cost is low, the production safety is high, and the obtained product has excellent stability and transdermal absorption performance.

The present application is directed to stabilized core-shell microcapsules comprising a core of benzoyl peroxide (BPO) or all trans retinoic acid (ATRA) and a metal-oxide shell; and to pharmaceutical compositions and methods of use thereof.

Provided herein are, inter alia, compositions, systems, and methods for preventing or treating acne. Included are compositions, combinations, systems, and methods comprising at least one Propionibacterium acnes bacteriophage, at least one anti-acne compound, and a pharmaceutically acceptable carrier. Also included are compositions, combinations, and systems comprising a Propionibacterium acnes bacteriophage and an enzyme. Methods for preventing or treating acne are also provided.