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Preparing method of traditional Chinese medicine composition tablet for curing wind-heat type cold

A wind-heat cold and composition technology, which is applied in the field of preparation of traditional Chinese medicine composition tablets, can solve the problems of low hardness, rough and mottled surface of tablet cores, affecting tableting efficiency and the like, and achieves good hardness, smooth and uniform appearance, The effect of short disintegration time

Active Publication Date: 2011-09-21
ZHANGZHOU PIEN TZE HUANG PHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the surface of the tablet core produced by the current preparation process is rough and mottled, and the hardness is low, which is only suitable for low-speed tableting, which seriously affects the tableting efficiency.

Method used

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  • Preparing method of traditional Chinese medicine composition tablet for curing wind-heat type cold
  • Preparing method of traditional Chinese medicine composition tablet for curing wind-heat type cold

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Embodiment 1: the preparation of tablet

[0051] API:

[0052] Honeysuckle 234g Vitex root 390g Guanzhong 234g

[0053] Sanchaku 234g Gourd Tea 234g Licorice 234g

[0054] peppermint oil 2ml

[0055] Preparation:

[0056] Take 1 / 3 honeysuckle and grind it into fine powder; add 6 times the weight of water to the other 2 / 3 honeysuckle, soak at 85°C for 1 hour, filter to get honeysuckle extract; Add licorice five flavors to decoct twice, add 6 times the weight of water for the first time, decoct for 2 hours, add 4 times the weight of water for the second time, decoct for 1 hour, filter, combine the decoction, and combine with the above honeysuckle extract , concentrated into a thick paste; add the above-mentioned honeysuckle fine powder, auxiliary materials and binders to make granules, boil and dry, granulate, spray peppermint oil, mix well, and press into tablets; wherein the auxiliary materials are starch: dextrin : Micropowder silica gel = 2: 1: 1, the adhesive is...

Embodiment 2

[0057] Embodiment 2: the preparation of tablet

[0058] API:

[0059] Honeysuckle 205g Vitex root 450g Guanzhong 300g

[0060] Sanchaku 210g Gourd Tea 300g Licorice 200g

[0061] peppermint oil 1ml

[0062] Preparation:

[0063]Take 1 / 4 honeysuckle and crush it into fine powder; add 7 times the weight of water to the other 3 / 4 honeysuckle, soak at 80°C for 0.5 hours, filter to get honeysuckle extract; Glycyrrhizae five flavors were decocted once with 7 times the weight of water, filtered, decocted for 3 hours, combined with the above honeysuckle extract, concentrated into a thick paste; added the above honeysuckle fine powder, auxiliary materials and binders to make granules, boiled and dried , granulated, sprayed with peppermint oil, mixed evenly, and pressed into tablets; wherein the auxiliary material is starch: dextrin: micropowder silica gel = 1.5: 1.5: 0.5, and the adhesive is starch slurry; both the auxiliary material and the adhesive are Regular use.

Embodiment 3

[0064] Embodiment 3: the preparation of tablet

[0065] API:

[0066] Honeysuckle 300g Vitex root 350g Guanzhong 220g

[0067] Sanchaku 290g Gourd Tea 205g Licorice 295g

[0068] peppermint oil 4ml

[0069] Preparation:

[0070] Take 1 / 2 honeysuckle, crush it into fine powder; add 5 times the weight of water to the other 1 / 2 honeysuckle, soak at 90°C for 2 hours, filter to get honeysuckle extract; Add water to decoct the five flavors of licorice and licorice 3 times, add 3 times the weight of water for the first time, decoct for 0.5 hours, add 4 times the weight of water for the second time, decoct for 1.5 hours, add 5 times the water for the third time, decoct for 2.5 hours hour, filter, combine the decocting solution, combine with the above-mentioned honeysuckle extract, concentrate into a thick paste; add the above-mentioned honeysuckle fine powder, auxiliary materials and binders to make granules, boil and dry, granulate, spray peppermint oil, mix uniform, compressed ...

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Abstract

The invention relates to a preparation method of a traditional Chinese medicinal composition tablet, and especially relates to a preparation method of a traditional Chinese medicinal composition tablet for curing wind-heat colds. According to the invention, the tablet prepared by the preparation method has a short disintegration time, a smooth and even appearance, and a good hardness, which enables the tablet suitable for high speed tablet compressing, thereby saving preparation time and substantially enhancing the quality of the tablets and production efficiency. According to a comparative study of the novel art and the prior art, it is obvious that the novel art is superior to the prior art.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine composition tablet, in particular to a preparation method of a traditional Chinese medicine composition tablet for treating anemopyretic cold. Background technique [0002] Jinmu Ganmao Tablets have the effects of dispelling wind, relieving the exterior, clearing heat and detoxifying, and its curative effect is remarkable. It is a commonly used medicine for treating exogenous wind-heat, fever, aversion to cold, headache, cough, and sore throat. However, the surface of the tablet core produced by the current preparation process is rough and mottled, and the hardness is low, which is only suitable for low-speed tablet compression, which seriously affects the tablet compression efficiency. Therefore, there is an urgent need to improve the existing preparation methods to improve drug quality and industrial production efficiency. Contents of the invention [0003] The purpose...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/85A61K9/20A61P11/00
Inventor 陈纪鹏洪绯吴亚滨刘冬英
Owner ZHANGZHOU PIEN TZE HUANG PHARM
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