Synergetic method for bacterial inhibition of ceftriaxone sodium by chitosan

A technology of ceftriaxone sodium and ceftriaxone sodium, which is applied in the field of biomedicine, can solve the problems of uncontrollable dosage, unclear biological toxicity, and high cost, and achieve the effect of reducing clinical diagnosis procedures, reducing burden and pain, and simple equipment
CN102198144AInactive Publication Date: 2011-09-28TONGJI UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
TONGJI UNIV
Publication Date
2011-09-28
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a synergetic method for bacterial inhibition of ceftriaxone sodium by chitosan. According to the method, a natural nontoxic macromolecular substance chitosan is added to the commercial ceftriaxone sodium to play a synergetic effect on the bacterial inhibition of the ceftriaxone sodium. Compared with the prior art, excellent synergetic bacterial inhibition of the ceftriaxone sodium is achieved by the chitosan, thus greatly reducing the dosage of the original ceftriaxone sodium, and achieving a better bacterial inhibition effect by a lower drug concentration.
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Description

technical field

[0001] The invention belongs to the field of biomedicine, and in particular relates to a synergistic synergistic method for chitosan on the antibacterial performance of ceftriaxone sodium. Background technique

[0002] With the increasing use of antibiotics, bacteria show varying degrees of drug resistance to some commonly used drugs. For those drugs that are used for a longer period of time and are used more widely, the drug resistance of bacteria tends to be more serious. Ceftriaxone sodium also faces the same problem as the third-generation cephalosporin antibiotics. The usual solution is to use β-lactamase inhibitors to make a compound preparation of β-lactam antibiotics or increase the concentration of antibiotics. dosage, but the problem is that no matter what organic ingredients are added or the dosage of the drug is increased, the side effects of the drug on the human body will also increase. At the same time, it will cause that the course of treatm...

Claims

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