Systems and methods for performing measurements of one or more materials
A subsystem and photosensitive detection technology, which is applied in the analysis of materials, measuring devices, and biological material analysis, etc., and can solve problems such as fragility and expensive instruments
Active Publication Date: 2015-06-24
LUMINEX
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- Description
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- Application Information
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Problems solved by technology
Although the performance of such systems is generally high, the price of these instruments is too expensive for some markets
In addition, the physical body of the flow cytometer is large, heavy and relatively fragile, and typically a trained technician must perform calibration of the flow cytometer on-site at the installation site
Method used
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[0027] Although some embodiments are described herein with respect to particles, beads, and microspheres, it should be understood that all systems and methods described herein can support particles, microspheres, polystyrene beads, microparticles, gold nanoparticles, Quantum dots, nanodots, nanoparticles, nanoshells, beads, microbeads, rubber particles, rubber beads, fluorescent beads, fluorescent particles, colored particles, colored beads, tissues, cells, microorganisms, organic matter, non-organic matter Or any other discontinuous material known in the art. Particles can be used as mediators for molecular reactions. Examples of suitable particles are described in the following U.S. Patent Numbers, the entire contents of which are incorporated herein by reference as if set forth herein: 5,736,330 to Fulton, 5,981,180 to Chandler et al. 6268222 to Chandler et al., 6449562 to Chandler et al., 6514295 to Chandler et al., 6524793 to Chandler et al., and 6528165 to Chandler et a...
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Abstract
Systems and methods for performing measurements of one or more materials are provided. One system is configured to transfer one or more materials to an imaging volume of a measurement device from one or more storage vessels. Another system is configured to image one or more materials in an imaging volume of a measurement device. An additional system is configured to substantially immobilize one or more materials in an imaging volume of a measurement device. A further system is configured to transfer one or more materials to an imaging volume of a measurement device from one or more storage vessels, to image the one or more materials in the imaging volume, to substantially immobilize the one or more materials in the imaging volume, or some combination thereof.
Description
technical field [0001] The present invention broadly relates to systems and methods for making measurements on one or more materials. In particular, the systems and methods of the present invention are configured to transfer one or more materials from one or more storage containers to an imaging volume of a measurement device, to one or more of the imaging volumes Multiple materials are imaged, one or more materials, or some combination thereof, are substantially immobilized in the imaging volume. Background technique [0002] The following descriptions and examples are not admitted to be prior art by inclusion in this section. [0003] Instruments commonly used in flow cytometry provide a viable system for measuring (or "interrogating") one or more characteristics of microspheres (or other particles) that are internally stained with fluorescent dyes, fluorophores, or fluorescent label coupling. Fluorescent dyes, fluorophores, or fluorescent tags coupled to microspheres c...
Claims
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IPC IPC(8): G01N15/10G01N15/14H04N25/00
CPCG01N21/274G01N21/645G01N33/54333G01N35/00693G01N35/00732G01N2015/1452G01N2035/00544G01N2035/00564G01N2201/1211G01N35/0098Y10T436/12G01N15/1433G01N21/05G01N33/54326B03C1/288B03C1/01G01N2021/0367G01N2021/058
Inventor 韦恩·D·罗特爱德华·A·卡尔维查尔斯·J·柯林斯威廉·R·戴歇尔亚尔登·E·克拉格亚当·R·席尔法特罗斯·G·约翰逊科林·D·博察尔特维克托·塞尔瓦拉杰埃里克·D·史密斯尼古拉斯·F·阿拉巴布鲁斯·J·C·伯纳德唐纳德·A·康纳罗贝特·S·罗奇大卫·L·史密斯
Owner LUMINEX