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Novel random multi-category full-automatic immunoassay system

An immune analysis, fully automatic technology, applied in the direction of analytical materials, instruments, biological testing, etc., can solve the problems of cumbersome operation, difficult online items, and few online testing items

Inactive Publication Date: 2013-09-04
SINNOWA MEDICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing fully automated immunoassay has a large and complex design structure, cumbersome operation, few online detection items, and slow speed. Generally, batch detection is performed, and the flexibility of detection items is poor.
Although there are also immunometers using micro-magnetic beads or plastic balls at present, compared with a random optional multi-item automatic immunoassay system of the present invention: there are different detection processes, it is difficult to expand a large number of online items, and it is inconvenient to store reagents. The problem of consumables / reagents is too much, so there are certain defects

Method used

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  • Novel random multi-category full-automatic immunoassay system

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Embodiment Construction

[0006] Below in conjunction with accompanying drawing, the present invention will be further described:

[0007] A random optional multi-item automatic immune analysis system designed by the present invention, the system uses magnetic plastic balls as solid-phase carriers, and the plastic balls are coated with different antigens or antibodies according to the detection purpose to become immune beads , using the principle of antigen-antibody reaction to bind the detected antibody or antigen to the surface of the immunobeads, and through the biotin and avidin amplification system, use the enzymatic chemiluminescence method or directly label the chemiluminescent substance to detect the luminescent signal to achieve the purpose of detection. The whole process is fully automated. Prepare various immune beads and place them in special jars respectively. When in use, place the opening downward on the specially designed immune bead plate 12 on the instrument. One immune bead plate can...

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Abstract

The invention discloses a novel random multi-category full-automatic immunoassay system. The novel random multi-category full-automatic immunoassay system comprises immunomagnetic beads, reagents and an automatic analyzer. A detection flow adopting the novel random multi-category full-automatic immunoassay system comprises the following steps of putting needed immunomagnetic beads into a reaction cup according to detection categories, adding respectively a sample, reagents and the like into the reaction cup according to a detection program, wherein before addition of each one of the reagents, the immunomagnetic beads and the reaction cup all are cleaned thoroughly, and detecting signals such as light and the like produced immunoconjugates so that a detection purpose is realized. A reaction disk can control a temperature according to detection temperature requirements. During cleaning, the novel random multi-category full-automatic immunoassay system can produce a magnetic field to enable the immunomagnetic beads to suspend or to float up and down, so that good cleaning effects are obtained and a cleaning needle can reach directly and easily to the bottom of the reaction cup to remove residual liquid by suction. After the detection flow is finished, the immunomagnetic beads are taken out by an immunomagnetic beads a removal arm and are abandoned, and the reaction cup is cleaned up and is utilized for the next detection flow. The novel random multi-category full-automatic immunoassay system can push forward immunomagnetic beads or a shakeable reaction disk by a magnetic force to promote full contact between reactants so that reaction sensitivity is improved.

Description

technical field [0001] A random optional multi-item automatic immune analysis system is a fully automatic instrument that can randomly and randomly detect up to dozens of immune test items and complete the measurement, belonging to medical and immunological detection automatic instruments field. Background technique [0002] Immunological detection is very important in disease diagnosis and has been widely used in the diagnosis of infectious diseases, tumors, endocrine and other diseases. In addition, it is also widely used in many fields such as agriculture, pharmaceuticals, food, environment and life sciences. In actual immunological testing, it is often necessary to perform multiple or even dozens of immune items on the same sample. However, the existing fully automated immunoassay has a large and complex design structure, cumbersome operation, few online detection items, and slow speed. Generally, batch detection is performed, and the flexibility of detection items is p...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N35/00G01N33/53
Inventor 徐新王礼文
Owner SINNOWA MEDICAL SCI & TECH