Human bladder cancer cell line

Abstract

The invention relates to a human bladder cancer cell line (of which the collection number is CCTCC (China Center for Type Culture Collection) NO. C201180) and a transfer cell line. The human bladder cancer cell line and the transfer cell line have important significance for transfer mechanisms and diagnosis and treatment of bladder cancer and provide suitable research materials for experimental researches.

Description

technical field [0001] The invention belongs to the field of animal cell lines, in particular to human bladder cancer cell lines. Background technique [0002] Bladder cancer is one of the most common urological tumors, which directly threatens the survival of patients. Worldwide, there were 386,300 new cases of bladder cancer in 2008, and 150,200 patients died of bladder cancer. In the United States, there were 70,530 new cases of bladder cancer in 2010, of which 14,683 died from bladder cancer. In my country, the incidence of male bladder cancer ranks eighth among all tumors in the body, and females rank after the twelfth. Although the incidence rate is much lower than that in western countries, in recent years, reports on the incidence of bladder cancer in some cities in my country have shown that the incidence of bladder cancer rate tends to increase. [0003] Bladder cancer can be divided into two main types: muscle invasive and non-muscle invasive. 70%-80% of newly ...

AI Technical Summary

Problems solved by technology

However, the latter is very prone to local invasion or distant metastasis. Although total cystectomy and lymph node dissection are performed, the patient is often difficult to cure, which is the main cause of patient death.

[0004] At present, the mechanism of organ metastasis of malignant tumors including bladder tumors is not clear, and patients with advanced tumors are often not suitable for surgery, which makes it difficult to obtain organ metastases, and the diagnosis, treatment and mechanism research of metastatic tumors is relatively lagging behind.

Images