Correlation interferometric methods, devices and systems for low cost and rugged spectroscopy

一种相关干涉、设备的技术,应用在干涉光谱法、相关光谱法、光学辐射测量等方向

Active Publication Date: 2012-03-07
RARE LIGHT
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  • Abstract
  • Description
  • Claims
  • Application Information

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If this could be done, instruments with such parts would be more durable

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  • Correlation interferometric methods, devices and systems for low cost and rugged spectroscopy
  • Correlation interferometric methods, devices and systems for low cost and rugged spectroscopy
  • Correlation interferometric methods, devices and systems for low cost and rugged spectroscopy

Examples

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Embodiment 1

[0078] Example 1 Detection of Glucose Level in Human Tissue

[0079] The devices, systems, methods and kits of the invention may, for example, be used to detect glucose levels in human tissue. The patient's skin surface is placed in the system and then irradiated with a beam of electromagnetic radiation. The beam is reflected off the skin and carries correlations representing absorption and wavelength indicative of the user's blood glucose level. The signal at the detector, together with the same signal after passing through the delay line, is input to an autocorrelator which determines the degree of correlation between the two signal paths. Subsequently, the strength of the correlation as a function of delay time yields a time series that can be related spectrally by Fourier transform. This spectrum can then be interpreted chemometrically to determine glucose levels in skin tissue samples.

[0080] When a sample is probed, for example, in a laboratory setting, and the spec...

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Abstract

A correlation interferometric spectroscopy devices are described that detect the spectral characteristics of a sample wherein device consists of an electromagnetic radiation source for exciting a sample with photons; and a detector adapted to detect an arrival time of a photon at the detector and further adapted to detect a delay between the arrival time of different photons. The device may further consist of an autocorrelator adapted to analyze the between the arrival of photons at the detector. The device may also be used together with other spectral detection and characterizing systems, such as Raman spectroscopy and attenuated total reflectance spectroscopy. Also provided herein are methods, systems, and kits incorporating the correlation interferometric spectroscopy device.

Description

[0001] cross reference [0002] This application claims the benefit of US Provisional Patent Application No. 61 / 146,166, filed January 21, 2009, which is hereby incorporated by reference. technical field [0003] The measurement of the electromagnetic correlation of optical wavelengths can be done both electrically and optically by measuring the delay between the arrival of photons at high-speed detectors. This field of study is known as correlation interferometry and is the subject of the present disclosure. Background technique [0004] Interferometers used in spectrometers are instruments that require high precision during manufacture. Must be fitted and maintained with an accuracy much smaller than the wavelength. While such tolerances are common in today's optical structures, it is prohibitively expensive to fabricate instruments that meet such small tolerances, especially if one or more components must be moved while maintaining this accuracy, such as scanning Miche...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01J3/45
CPCG01J3/4531G01J3/457G01N21/45G01N21/552G01N21/65G01J3/45
Inventor 罗伯特·G·梅塞施米特
Owner RARE LIGHT
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