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Dangshen extract pellet and preparation method thereof

The technology of extract and Codonopsis pilosula is applied in the field of pellets made of Codonopsis pilosula and its preparation field, which can solve the problems of long disintegration time, gastric mucosa irritation, low bioavailability and the like, achieves good effectiveness and reduces taking The number of times, the obvious effect of the release curve

Inactive Publication Date: 2012-05-23
JF PHARMALAND TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the products of Codonopsis pilosula extract are gradually being recognized by consumers. These products are basically ordinary tablets and capsules, but the above-mentioned dosage forms have a long disintegration time; The mucous membrane is irritating to a certain extent; the disadvantages such as low bioavailability

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] A pellet preparation of Codonopsis pilosula extract, the pharmaceutical excipients are excipients and binders, wherein in the pellet preparation Codonopsis pilosula extract is 35% by weight, the excipient is 64% by weight, and the adhesive The percentage composition of agent is 1%, prepares qualified micropill preparation.

Embodiment 2

[0048] A pellet preparation of Codonopsis pilosula extract, the pharmaceutical excipients are excipients and binders, wherein the pellet preparation has 60% by weight of Codonopsis pilosula extract, 32% by weight of excipients, and the adhesive The percentage content of agent is 8%.

Embodiment 3

[0050] A pellet preparation of Codonopsis pilosula extract, the pharmaceutical excipients are excipients and binders, wherein the pellet preparation has a weight percentage of Codonopsis pilosula extract of 40%, an excipient of 56% by weight, and the adhesive The percentage of agent is 4%.

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PUM

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Abstract

The invention provides a dangshen extract pellet preparation, which is prepared from a dangshen extract and pharmaceutical adjuvants, and is characterized in that: an excipient and a bonding agent are taken as the pharmaceutical adjuvants; and the pellet preparation comprises the following components in percentage by weight: 30-70 percent of a dangshen extract, 20-65 percent of an excipient and 1-10 percent of a bonding agent. The pellet preparation can be prepared into a slow-release or enteric preparation as required. As proved by a pharmacological experiment, the pellet disclosed by the invention has the effects of tonifying middle-jiao and qi, invigorating the spleen, promoting the production of body fluid, and the like.

Description

technical field [0001] The invention relates to the technical field of medicine and food, in particular to a pellet made of Codonopsis pilosula extract and a preparation method thereof. Background technique [0002] Codonopsis pilosula (Franch.) Nannf., Codonopsis pilosula Nannf.var.modesta (Nannf.) L.T.Shen or Codonopsis tangshen Oliv. Codonopsis tangshen Oliv. Its main chemical components are lactones and polysaccharides. Sexual flat, sweet in the mouth. The function is to invigorate the middle and replenish qi, invigorate the spleen and promote fluid production. For weak spleen and lung, shortness of breath and palpitation, lack of food and loose stools, fatigue of limbs. [0003] At present, the products of Codonopsis pilosula extract are gradually being recognized by consumers. These products are basically ordinary tablets and capsules, but the above-mentioned dosage forms have a long disintegration time; The mucous membrane is irritating to a certain extent; the bi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/344A61K9/16A23L1/29A61P1/14A23L33/00
Inventor 魏洪君
Owner JF PHARMALAND TECH DEV
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