Application of 3-(3,4-dihydroxycinnamoyl) quinic acid to preparation of medicines or food for preventing and treating ovulation disorder

A chlorogenic acid, barrier technology, applied in the field of medicine, can solve problems such as adverse side effects

Inactive Publication Date: 2012-07-04
KUNMING INST OF BOTANY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chlorogenic acid has a wide range of biological activities, and there are no reports of any adverse side effects of chlorogenic acid on the human body, so it is a Chinese medicine ingredient with great potential for development
So far, there are no reports in the prior art that chlorogenic acid can protect ovaries, promote ovulation, and treat ovulation disorders

Method used

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  • Application of 3-(3,4-dihydroxycinnamoyl) quinic acid to preparation of medicines or food for preventing and treating ovulation disorder
  • Application of 3-(3,4-dihydroxycinnamoyl) quinic acid to preparation of medicines or food for preventing and treating ovulation disorder
  • Application of 3-(3,4-dihydroxycinnamoyl) quinic acid to preparation of medicines or food for preventing and treating ovulation disorder

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Chlorogenic acid is routinely added with water for injection, finely filtered, potted and sterilized to make injection.

Embodiment 2

[0031] Dissolve chlorogenic acid in sterile water for injection, stir to dissolve, filter with a sterile suction filter funnel, then aseptic fine filter, divide into 2 ampoules, sterilize and melt seal to obtain a powder injection after low-temperature freeze-drying.

Embodiment 3

[0033] The excipient is added according to the weight ratio of the chlorogenic acid and the excipient at a ratio of 9:1 to prepare a powder.

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PUM

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Abstract

The invention relates to application of 3-(3,4-dihydroxycinnamoyl) quinic acid to the preparation of medicines and functional food for protecting an ovarian function, promoting ovulation and treating ovulation disorder. The 3-(3,4-dihydroxycinnamoyl) quinic acid can be prepared into medicinal preparations of various forms which comprise oral administration, injection and pulmonary inhalation preparations and transdermal preparations and particularly comprise injections, oral liquid, tablets, capsules, granules, aerosols, powder aerosols, pressurized sprays, patches and the like.

Description

Technical field: [0001] The invention belongs to the technical field of medicines, and specifically relates to the application of chlorogenic acid in the preparation of medicines or food for protecting ovaries, promoting ovulation and treating ovulation disorders. technical background: [0002] Ovulation disorder, also known as anovulation, is a major factor causing infertility, accounting for 25-30% of female infertility factors. With the strengthening of work intensity, the increase of mental pressure, the deterioration of the environment and unhealthy lifestyle, the incidence of ovulation disorders is increasing. In addition to causing infertility, ovulation disorders can also lead to menstrual disorders, amenorrhea, hirsutism, obesity and other symptoms. In addition, due to long-term anovulation, sex hormone metabolism disorder, endometrial hyperplasia without periodic progesterone antagonistic effect, it is easy to induce endometrial cancer and breast cancer. Therefor...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/216A61P15/08A61P15/00A23L1/29A23L33/00
Inventor 罗怀容杨洁郑善清吴桂生
Owner KUNMING INST OF BOTANY - CHINESE ACAD OF SCI
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