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Nasal preparation for treating epilepsy

A technology for nasal preparations, applied in the field of nasal preparations for the treatment of epilepsy, which can solve the problems that injections are not suitable for storage and carrying, and difficult to apply, and achieve the effect of treating and preventing epileptic seizures, and being convenient to carry and use

Inactive Publication Date: 2012-12-26
伍丽娟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In view of the actual situation of epileptic patients during seizures, common oral preparations are difficult to apply, and injections are not suitable for storage and carrying

Method used

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  • Nasal preparation for treating epilepsy
  • Nasal preparation for treating epilepsy
  • Nasal preparation for treating epilepsy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The nasal spray prescription of embodiment 1 solution type

[0022]

[0023] Make up 1000ml liquid medicine.

[0024] Preparation method: add water to the above main ingredients and auxiliary materials to 1000ml, mix, stir, stand still, and filter to obtain.

Embodiment 2

[0025] Embodiment 2 Gel type nasal spray prescription

[0026]

[0027] Make up 1000ml liquid medicine.

[0028] Preparation method: add water to the above main ingredients and auxiliary materials to 1000ml, mix well, stir, add bayberry essence, stir while adding, add a small amount of acetic acid to adjust the pH value of the solution to 4.0, let stand, stir well and filter to get ready.

Embodiment 3

[0029] Embodiment 3 Suspension type nasal spray prescription

[0030]

[0031] Make up 1000ml liquid medicine.

[0032] Preparation method: add water to the above main ingredients and auxiliary materials to 1000ml, mix well, stir and stand still, add a small amount of acetic acid to adjust the pH value of the solution to 4.5, stir well and filter to obtain.

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PUM

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Abstract

The invention relates to a nasal preparation for treating epilepsy. The nasal preparation comprises a liquid preparation (nasal drops, nasal spray, collunarium), a nasal semisolid preparation (nasal smearing paste) and a nasal solid preparation (nasal powder). The nasal preparation comprises a main drug of an M receptor antagonist, such as the substituted hydroxyl phenylacetic acid (N-substituted bicyclic [3, 3, 1] nonane ester) and substituted hydroxyphenyl ethyl (N-substituted bicyclic [3, 3, 1] nonane ether). The nasal drug preparation is convenient to carry and use, and can be effectively treat and prevent seizure disorders.

Description

technical field [0001] The invention relates to a nasal preparation for treating epilepsy, comprising nasal liquid preparation (nasal drops, nasal spray, nasal wash), nasal semi-solid preparation (nasal ointment) and nasal solid preparation (nasal powder) )Wait. The main drugs of nasal preparations are M receptor antagonists, such as substituted hydroxyphenylacetic acid (N-substituted bicyclo[3.3.1]nonyl ester) and substituted hydroxyphenethyl (N-substituted bicyclo[3.3.1] ] nonanyl ether). The nasal pharmaceutical preparation is convenient to carry and use, and can effectively treat and prevent epileptic seizures. Background technique [0002] Epilepsy is a serious neurological disorder characterized by seizures. The clinical manifestations of epilepsy are short-term sensory disturbance, limb twitching, loss of consciousness, behavioral disturbance or autonomic dysfunction, which are called epileptic seizures. Different types of epilepsy have different clinical symptoms....

Claims

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Application Information

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IPC IPC(8): A61K45/00A61K31/439A61P25/08
Inventor 伍丽娟
Owner 伍丽娟
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