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Methods and apparatus for renal neuromodulation via stereotactic radiotherapy

A stereotaxic, renal nerve technique, applied in radiation therapy, equipment for radiodiagnosis, ultrasound therapy, etc., can solve problems such as unsatisfactory blood pressure control rate treatment efforts

Inactive Publication Date: 2013-01-16
MEDTRONIC ARDIAN LUXEMBOURG SARL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Rates of blood pressure control and treatment efforts to prevent heart failure and chronic kidney disease and their sequelae remain unsatisfactory despite differing treatment options

Method used

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  • Methods and apparatus for renal neuromodulation via stereotactic radiotherapy
  • Methods and apparatus for renal neuromodulation via stereotactic radiotherapy
  • Methods and apparatus for renal neuromodulation via stereotactic radiotherapy

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Embodiment Construction

[0029] The present disclosure describes methods and devices for renal neuromodulation by stereotactic radiation therapy. Renal neuromodulation may be beneficial in the treatment of conditions or diseases associated with increased central sympathetic activation, including hypertension, heart failure, chronic kidney disease, insulin resistance, diabetes, metabolic syndrome, sleep apnea, atrial fibrillation, and / or or difficulty breathing.

[0030]While the disclosure is detailed and precise to enable those skilled in the art to practice the disclosed technology, the physical embodiments disclosed herein are merely illustrative of aspects of the invention, which may be embodied in other specific structures. Having described a preferred embodiment, details may be changed without departing from the invention as defined by the claims.

[0031] References in the specification to "one embodiment", "an embodiment", "an implementation" or "an implementation" mean that the specific feat...

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Abstract

The present disclosure describes methods and apparatus for renal neuromodulation via stereotactic radiotherapy for the treatment of hypertension, heart failure, chronic kidney disease, diabetes, insulin resistance, metabolic disorder or other ailments. Renal neuromodulation may be achieved by locating renal nerves and then utilizing stereotactic radiotherapy to expose the renal nerves to a radiation dose sufficient to reduce neural activity. A neural location element may be provided for locating target renal nerves, and a stereotactic radiotherapy system may be provided for exposing the located renal nerves to a radiation dose sufficient to reduce the neural activity, with reduced or minimized radiation exposure in adjacent tissue. Renal nerves may be located and targeted at the level of the ganglion and / or at postganglionic positions, as well as at pre-ganglionic positions.

Description

[0001] References to related applications [0002] This application claims the benefit of US Provisional Patent Application Serial No. 61 / 296,417, filed January 19, 2010, which is incorporated herein by reference in its entirety. technical field [0003] The technology disclosed herein relates generally to methods and devices for renal neuromodulation by stereotactic radiation therapy. Background technique [0004] Radiation therapy, or radiotherapy, involves directed beams of external radiation, which have been used for some time to treat cancer and a variety of other diseases to non-invasively destroy malignant tissue. Radiation therapy is delivered to the target tissue in a single procedure in a single segment (often called radiosurgery), or it can be delivered in multiple sessions using a multi-part approach. The radiation beam may be from an active radiation source, such as an alpha, beta, or gamma radiation source, or may be activated by a particle accelerator such as...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B6/00
CPCA61B2018/00404A61B2018/00511A61N2005/1061A61N7/02A61N5/1067A61N5/1042A61B2018/00434A61B6/506
Inventor R·J·比特尔N·C·巴曼B·J·克拉克P·弗里德里克斯K·J·米克利什K·D·纳加A·吴D·扎林司
Owner MEDTRONIC ARDIAN LUXEMBOURG SARL
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