Tinea pedis powder for treating tinea manuum, tinea pedis and onychomycosis and preparation method thereof

A technology for athlete's foot and onychomycosis, which is applied in the field of drug preparation, can solve the problems of large toxic and side effects, poor effect, etc., and achieve the effects of reducing tissue tension, promoting wound healing, and good therapeutic effect

Active Publication Date: 2013-03-13
唐伟东
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The object of the present invention is to provide a kind of tinea pedis powder and preparation method thereof for the treatment of tinea manuum, tinea pedis, tinea unguium, utilize its small toxic and side effects, remarkable therapeutic effect, the characteristics that patients are easy to accept, be used for the treatment of tinea pedis and tinea pedis and Tinea onychomycosis overcomes the disadvantages of existing drugs of the same kind, such as poor efficacy and large toxic and side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Get 150 grams of gypsum, 120 grams of dry alum, 1500 grams of borax, 220 grams of talcum powder, and 350 grams of zeolite after drying, put in a pulverizer to pulverize, the medicinal powder passes through a 120 mesh sieve, and mix well to obtain a mixed Chinese medicine powder for subsequent use. Then take 500 grams of benzoic acid, 20 grams of nitrofurazone, 800 grams of salicylic acid, and 100 grams of zinc oxide, grind them in a large mortar, sieve, regrind the coarse powder until all pass through a 120-mesh sieve, and mix well to obtain western medicine powder for later use. . Mix the mixed Chinese medicine powder and the mixed western medicine powder evenly, sieve 3-5 times to get the powder, and pack it into 40g / bag. When using, take 40 grams of powder and add 1500-2500 ml of boiling water, stir, dissolve, let it warm, soak the affected area for 20-30 minutes while it is hot, 2 times a day, 2 weeks as a course of treatment.

Embodiment 2

[0033]Take 120 grams of gypsum, 100 grams of dry alum, 1200 grams of borax, 200 grams of talcum powder, 300 grams of zeolite, 500 grams of benzoic acid, 22 grams of nitrofurazone, 750 grams of salicylic acid, and 150 grams of zinc oxide. The powder is ready for use; use Carbomer 940 as an excipient, add 5 ml of ethyl ester to the swollen 1000 g of Carbomer 940, stir evenly, heat to 80°C, then cool the solution to 30°C, Add 2-4 grams of the above-mentioned mixed medicinal powder to the ethyl ester solution of M940, stir and mix evenly to form a gel. The method of use is to apply externally to the affected area, 2 times a day, 2 weeks as a course of treatment.

Embodiment 3

[0035] Take 100 grams of gypsum, 100 grams of dry alum, 1500 grams of borax, 200 grams of talcum powder, 300 grams of zeolite, 500 grams of benzoic acid, 20 grams of nitrofurazone, 800 grams of salicylic acid, and 120 grams of zinc oxide, pulverize them through a 180-mesh sieve to obtain a mixed medicinal powder Standby; with lanolin, paraffin, vaseline as excipients. Mix lanolin, paraffin, and Vaseline in a weight ratio of 1:2:20, heat in a water bath until melted to form a compound lanolin ointment; then use a compound lanolin ointment:drug powder weight ratio of 5:6, and mix the two together Get an ointment evenly. When in use, directly apply the ointment to the affected area, twice a day, and 2 weeks is a course of treatment.

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PUM

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Abstract

The invention discloses tinea pedis powder for treating tinea manuum, tinea pedis and onychomycosis and a preparation method of the tinea pedis powder, solving the problems that antifungal drugs are always adopted and used for treating the tinea manuum, tinea pedis and onychomycosis in the clinic, which bring a certain treatment effect along with high side effects, and traditional Chinese medicine products for treating tinea manuum and tinea pedis are wide in varieties provided but are uncertain in treatment effects. The tinea pedis powder is prepared by the following components by weight: 50 to 80 parts of salicylic acid, 100 to 150 parts of borax, 30 to 50 parts of benzoic acid, 1 to 3 parts of nitrofurazone, 10 to 20 parts of zinc oxide, 10 to 20 parts of gypsum, 10 to 20 parts of dried alum, 20 to 30 parts of talcum powder, and 30 to 40 parts of zeolite. According to the tinea pedis powder, raw Western medicines are good in antifungal effects, and raw traditional Chinese medicines have effects of generating far infrared radiation, and the raw Western medicines and the raw traditional Chinese medicines can be combined to reach dual functions and bring remarkable medical effects in treating tinea manuum, tinea pedis and onychomycosis; and as the clinical test shown, the tinea pedis powder applied to 803 patients with tinea manuum, tinea pedis and onychomycosis gives the results that the total effective rates of the treatment group and the control group are respectively 100% and 88.5%, and P is less than 0.05 by making a comparison between the two groups.

Description

technical field [0001] The invention relates to tinea pedis powder for treating tinea manuum, tinea pedis and tinea unguium and a preparation method thereof, especially the tinea pedis powder prepared by combining Chinese and Western medicines, belonging to the technical field of medicine preparation. Background technique [0002] Tinea manuum, tinea pedis and onychomycosis are superficial fungal infectious diseases caused by dermatophytes invading palms, soles, interdigital (toe) epidermis and finger (toe) nails. Commonly known as tinea manuum as "swan palm wind". Tinea pedis is "athlete's foot", and tinea unguium is "onychomycosis". The three can often infect each other and come on one after another, or they can only invade one place and occur alone. Wherein the most common with tinea pedis, is the highest incidence rate in fungal diseases. In the south of the Jianghuai River Basin in my country, in humid and warm areas, the adult prevalence rate in summer reaches 50-60...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/30A61P17/00A61P31/10A61K31/192A61K31/345A61K31/60A61K33/06A61K33/12A61K33/22
Inventor 唐伟东潘忠艳
Owner 唐伟东
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