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Composition for preventing or treating pruritus cutanea

A technology for skin pruritus and complex, which is applied in the field of complex to achieve the effect of high-efficiency prevention or treatment and good therapeutic effect

Active Publication Date: 2013-03-27
BEIJING UNIV OF CHEM TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report on biomedical polymer hydrolyzate (such as hydrolyzed collagen, etc.) as the prevention and treatment of skin pruritus, let alone these molecules (such as hydrolyzed collagen, etc.) as active components for the prevention and treatment of skin pruritus report

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] Formula: The total amount of hydrolyzed collagen, chlorohydrin, allantoin, propylene glycol and hyaluronic acid is 0.75g (the mass ratio of the three is 10:3:2), stearyl alcohol is 8.5g, white oil is 3g, polydimethylformaldehyde 4.5g silicone, 3g isooctyl palmitate, 8g glycerin, 1g glyceryl monostearate, 0.60g nonylphenol polyoxyethylene ether, 0.40g sodium lauryl sulfate, 0.5g essence, appropriate amount of preservative , add water to 100g.

[0061] Process: Mix hydrolyzed collagen, chlorohydrazine allantoin, propylene glycol, and hyaluronic acid in the above ratio, then mix and emulsify with other components except fragrances at 90°C for 30 minutes, and then mix and emulsify at a temperature of 1 The temperature is lowered at a rate of 1°C, and when the temperature drops to 55°C, spices are added, and the product can be obtained after emulsification.

Embodiment 2

[0063] Formula: the total amount of hydrolyzed collagen, chlorohydrin, allantoin, propylene glycol and hyaluronic acid 1.00g (the mass ratio of the three is 15:6:6), stearyl alcohol 8.5g, white oil 3g, polydimethylform 4.5g silicone, 3g isooctyl palmitate, 8g glycerin, 1g glyceryl monostearate, 0.60g nonylphenol polyoxyethylene ether, 0.40g sodium lauryl sulfate, 0.5g essence, appropriate amount of preservative , add water to 100g.

[0064] Process: except that formula is different, other process conditions are identical with embodiment 1.

Embodiment 3

[0066]Formula: The total amount of hydrolyzed bone collagen, chlorohydroxy aluminum allantoin, propylene glycol and hyaluronic acid is 3.00g (the mass ratio of the three is 5:1:1), stearyl alcohol 8.5g, white oil 3g, polydimethylform 4.5g silicone, 3g isooctyl palmitate, 8g glycerin, 1g glyceryl monostearate, 0.60g nonylphenol polyoxyethylene ether, 0.40g sodium lauryl sulfate, 0.5g essence, appropriate amount of preservative , 0.02g of di-tert-butyl-4-methylphenol (BHT), 0.02g of diazolidinyl imidazolium (Extreme II), 0.05g of disodium EDTA, add water to 100g.

[0067] Process: except that formula is different, other process conditions are identical with embodiment 1.

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Abstract

The invention discloses a composition for preventing or treating pruritus cutanea. The composition comprises the following active components: (1) hydrolyzed collagen, (2) hyaluronic acid and (3) allantoin compound, wherein the allantoin compound is allantoin and / or allantoin aluminum compound. The compound disclosed by the invention can be used for effectively preventing or treating the pruritus cutanea, and particularly shows a good effect on treating senile pruritus.

Description

technical field [0001] The invention relates to a compound for preventing or treating pruritus, in particular to a hydrolyzed collagen compound for preventing or treating pruritus. Background technique [0002] The skin is the largest organ of the human body and the first line of defense of the human body. Skin health is the key to maintaining human health, and it is also a manifestation of beautifying the skin. At present, there are many kinds of skin diseases, and it is easy to come into contact with toxic substances and bacteria, so the protection of the skin is very important. At present, the incidence of skin pruritus is relatively high, but there is no good external medicine to prevent and treat it. Usually, skin pruritus refers to the absence of primary rash, which is a skin neurosis disorder. Pruritus commonly occurs all over the body, or on the face, back, or extremities. Typically, pruritus is associated with skin that is too dry or chapped. [0003] The Chines...

Claims

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Application Information

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IPC IPC(8): A61K38/39A61P17/04A61K31/4166A61K31/728
Inventor 黄雅钦闵新宇刘伟刘秀芳潘炳雄
Owner BEIJING UNIV OF CHEM TECH
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