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Drug composition, preparation method and application thereof

A technology of composition and medicine, applied in the field of pharmaceutical composition and its preparation, to achieve obvious effects of prevention and treatment

Inactive Publication Date: 2015-08-05
GUANGZHOU BAIYUNSHAN ZHONGYI PHARMA COMPANY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Existing studies have found that there is a certain relationship between anti-oxidation and the treatment of diabetic complications, but there is no drug or health product that has the functions of anti-oxidation and prevention of diabetic complications at the same time

Method used

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  • Drug composition, preparation method and application thereof
  • Drug composition, preparation method and application thereof
  • Drug composition, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Embodiment 1 Preparation of the pharmaceutical composition of the present invention

[0039] 1. Preparation of raw and auxiliary materials

[0040] ① Preparation of raw materials: 50kg of Astragalus membranaceus and 40kg of Anemarrhena anemarrhena have passed the inspection, removed impurities, washed, sliced, and set aside; 10kg of Cordyceps militaris fruiting bodies have passed the inspection, removed impurities for later use; 40ml of peppermint oil has been tested and set aside for later use.

[0041] ② Preparation of auxiliary materials: 10% steviol glycoside solution, 10% potassium sorbate solution, and purified water are passed the appropriate amount of inspection, and then moved into the clean area for standby;

[0042] 2. Preparation of the pharmaceutical composition of the present invention

[0043]① Put Astragalus and Anemarrhena in a multi-functional extraction tank, add water to extract twice, add 8 times the amount of water for the first time, decoct for 2...

Embodiment 2

[0047] Embodiment 2, the antioxidant function experiment of pharmaceutical composition of the present invention (aged mice)

[0048] The pharmaceutical composition prepared in Example 1 is rich in polysaccharides, polyphenols, saponins and other substances. The free radical theory of aging holds that cell aging caused by free radicals and lipid peroxides is an important cause of aging. The activity of antioxidant enzymes in the body is enhanced, the ability to scavenge free radicals is enhanced, and its anti-aging ability is also enhanced. In this experiment, an aging mouse model was established, and the pharmaceutical composition prepared in Example 1 was used to intervene to observe its effect on the antioxidant function of aging mice.

[0049] 1 Materials and methods

[0050] 1.1 Sample: The pharmaceutical composition prepared in Example 1, 20ml / bottle, packed in a glass bottle, the content is a tan liquid, stored in a cool and dry place.

[0051] 1.2 Experimental animal...

Embodiment 3

[0100] Experimental research on the prevention and treatment of diabetic complications by the pharmaceutical composition of embodiment 3 and embodiment 1

[0101] Diabetes is a comprehensive disease characterized by persistent high blood sugar as its basic biochemical feature. With the prolongation of the disease course, it will lead to the occurrence of chronic complications in tissues and organs such as eyes, kidneys, nerves, blood vessels, heart and skin, and even endanger life. Diabetes The pathogenesis of diabetes and its complications is not yet very clear, but the number of diabetic patients is on the rise and gradually getting younger. Therefore, prevention of diabetes and its complications is very important. Traditional Chinese medicine has been paid more and more attention by researchers at home and abroad because of its characteristics of treating both symptoms and root causes and having few side effects. In this experiment, by establishing an animal model of diabe...

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Abstract

The invention discloses a drug composition, a preparation method and an application thereof, wherein active components of the drug composition comprise following raw materials, by weight: 45-55 parts of astragalus membranaceus, 35-45 parts of rhizoma anemarrhenae, 5-15 parts of fruiting bodies of cordyceps militaris and 0.03-0.05 parts of dementholized peppermint oil. The drug composition can be used for preparing health-caring products or medicines having effects of resisting oxidization and delaying senescence, and also can be used for preparing medicines for preventing and treating diabetic complications.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a pharmaceutical composition and its preparation method and application. Background technique [0002] Free radicals are atoms, molecules or groups that contain unpaired electrons and are highly active. Free radicals are normal metabolites of the human body. Under normal circumstances, free radicals in the human body are in a dynamic balance of continuous generation and removal. There are a small amount of oxygen free radicals in the human body, which not only pose no threat to the human body, but also promote cell proliferation and stimulate White blood cells and phagocytes kill bacteria, eliminate inflammation, and break down toxins. If there are too many free radicals [reactive oxygen species (ROS)] in the body, the antioxidant capacity will decrease and a chain reaction will be triggered. This process is oxidation. Free radicals are produced too much or...

Claims

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Application Information

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IPC IPC(8): A61K36/8964A61P39/06A61P3/10A23L1/29A23L33/00
Inventor 李吉来张春波邹琦耿春贤周杰程艳阳梁海清王尉
Owner GUANGZHOU BAIYUNSHAN ZHONGYI PHARMA COMPANY
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