Method for coating stationary phase in capillary column

A technology of capillary column and stationary phase, which is applied in the direction of measuring devices, instruments, scientific instruments, etc., can solve the problem that it is difficult to form uniform thickness, and achieve the effect of good thickness uniformity

Inactive Publication Date: 2013-05-08
TIANJIN KERMEL CHEM REAGENT
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the prior art, a small amount of air is dissolved in the coating solution. If the stationary phase is not treated, it is difficult to form a film with uniform thickness after drying, so that the coating success rate is only about 10%.

Method used

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  • Method for coating stationary phase in capillary column
  • Method for coating stationary phase in capillary column

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Embodiment Construction

[0016] Referring to accompanying drawing, in order to realize the coating device that coating method of the present invention adopts comprises the airtight container 1 that is used to hold coating liquid 2, this airtight container 1 top is provided with plug-in port, and this plug-in port is filled with elastic sealing plug 4, The elastic sealing plug 4 is provided with a through hole for inserting the capillary column 5 , and the inner wall of the through hole is in interference fit with the outer wall of the capillary column 5 to be processed.

[0017] The top of the airtight container 1 can also be provided with a sealing cover 3, the sealing cover 3 is closed during use, and the coating liquid 2 is convenient to be filled when the sealing cover 3 is opened. Good airtightness is ensured after the capillary column 5 is inserted, and the elastic sealing plug 4 can be made of a material that does not react with the coating liquid, such as tetrafluoroethylene.

[0018] When usi...

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Abstract

The invention discloses a method for coating a stationary phase in a capillary column. The method comprises the following steps: 1, filling a coating liquid into a closed container, wherein the closed container only has a top outlet, and the top outlet is communicated with the first port of two ports of the capillary column; 2, heating the coating liquid in the closed container to make volatile matters in the coating liquid enter the first port of the capillary column and be discharged from the second port of the capillary column; 3, inserting the first port of the capillary column into the coating liquid after the coating liquid is boiling until the coating liquid enters and fills up the capillary column; and 4, closing the second port of the capillary column, pulling the first port of the capillary column out of the closed container, and carrying out vacuum drying of the coating liquid in the capillary column until residues form a stationary phase at the inner wall of the capillary column. The coating method allows the degassing and perfusion of the coating liquid to be once completed, so the coating success rate of the stationary phase of the capillary column is improved to above 95%, and the thickness homogeneity of the formed stationary phase is good.

Description

technical field [0001] The invention relates to a method for pouring and coating a stationary phase into a capillary column. Background technique [0002] Capillary chromatographic columns are widely used in the field of analysis and detection. Capillary chromatographic columns are mainly composed of glass or metal capillary columns and related accessories. The inner wall of the capillary column is coated with a stationary phase, and its performance has a key impact on the detection effect. [0003] During processing, the stationary phase is generally dissolved or dispersed in an organic solvent to form a coating solution, and then the coating solution is poured into the capillary column, and then vacuum-dried to coat the stationary phase material on the inner wall of the capillary column. [0004] In the prior art, a small amount of air is dissolved in the coating solution. If the stationary phase is not treated, it is difficult to form a film with uniform thickness after d...

Claims

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Application Information

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IPC IPC(8): G01N30/56
Inventor 寇登民刘振荣
Owner TIANJIN KERMEL CHEM REAGENT
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