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Medicinal composition for treating chronic gastritis and its preparation method

A technology for chronic gastritis and composition, applied in the field of pharmaceutical compositions, can solve the problems of less obvious effect of Chinese patent medicine and large side effects of western medicine, and achieve the effects of no toxic side effect, remarkable effect and remarkable treatment.

Active Publication Date: 2014-07-02
CP PHARMA QINGDAO CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many medicinal compositions for the treatment of chronic gastritis, the side effects of Western medicine are large, and the effect of Chinese patent medicine is not obvious

Method used

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Examples

Experimental program
Comparison scheme
Effect test

experiment example

[0025] 1. Clinical observation

[0026] Treatment group 1 selected capsules of the present invention (prepared according to the method of Example 1) to treat 100 patients with chronic gastritis, including 50 males and 50 females.

[0027] Treatment group 2 selected the tablet of the present invention (prepared according to the method of Example 2) to treat 100 patients with chronic gastritis, including 50 males and 50 females.

[0028] Treatment group 3 selected granules of the present invention (prepared according to the method of Example 3) to treat 100 patients with chronic gastritis, including 50 males and 50 females.

[0029] The control group used Danguixiang Capsules, produced by Shaanxi Dongtai Pharmaceutical Co., Ltd., to treat 100 patients with chronic gastritis, including 50 males and 50 females.

[0030] 2. Drug selection

[0031] Treatment group 1: capsules of the present invention (prepared according to the method of Example 1), one course of treatment (one cou...

experiment example 2

[0052] Experimental example two, pharmacodynamics test

[0053] 1. Test material

[0054] 1.1 Experimental animals: Kunming mice, half male and half female, weighing 18-22g, all experimental animals were purchased from the Experimental Animal Center of Soochow University.

[0055] The mice were in groups of 6-10 and were kept in plastic mouse cages. During the whole experiment period, the animals had free access to food and water, and the experimental animals were adaptively fed for at least three days before the experiment.

[0056] 1.2 Grouping and administration: choose 50 small animals and divide them into 5 groups at random, blank control group, Danguixiang capsule control group, drug dose I group of the present invention, drug dose II group of the present invention and drug dose III group of the present invention. The drug dose group I of the present invention (prepared according to the method of Example 1); the drug dose group II of the present invention (prepared acco...

Embodiment 1

[0071] Embodiment 1 capsule

[0072] Guizhi 20kg Evodia 60kg Curcuma 30kg

[0073] Leech 20kg Salvia 40kg.

[0074] Add 15 times the amount of water to the four raw materials except leeches, soak for 36 hours; decoct twice with a slow fire, the first time is 2 hours, filter the medicinal liquid for later use, add 10 times the amount of water for the second time, Decoct with slow fire for 1 hour, filter out the medicinal liquid for use; combine the secondary medicinal liquid for filtration, and collect the filtrate; concentrate the filtrate to a thick paste with a relative density of 1:1.25-1.35, set aside, stir-fry the leech for 8 minutes, Grind into fine powder and mix with the above thick paste, bake the thick paste at low temperature for 10 hours to obtain dry paste powder, add dry paste powder and starch at a weight ratio of 1:0.5, add auxiliary materials, granulate, dry at 50°C, and granulate Then divide into capsules. Capsule specification: 0.3g / capsule, 3 times a day...

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Abstract

The invention discloses a medicinal composition for treating chronic gastritis and its preparation method. The composition consists of cassia twigs, Evodia rutaecarpa, Curcuma Zedoary, leeches and Salvia miltiorrhiza. By subjecting the medicinal composition to decocting, filtering, concentrating, drying and other steps and adding a conventional auxiliary material, a clinically acceptable tablet, capsule, granule, pill or oral liquid can be obtained. The medicinal composition provided in the invention has a significant treatment effect on chronic gastritis, and has no toxic or side effect.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for treating chronic gastritis and a preparation method thereof. Background technique [0002] Chronic gastritis is mainly a gastrointestinal disease caused by spleen-stomach deficiency and blood stasis caused by cold. Or gluttony for raw and cold food, damage to the spleen, resulting in a deficiency of spleen yang that cannot warm the stomach and intestines, and cold air is born from the inside. Chronic gastritis, peptic ulcer, duodenitis, malabsorption syndrome, and ulcerative colitis often occur or are accompanied by chronic gastritis syndrome. Symptoms of spleen and stomach deficiency and cold are often caused by cold weather and cold food, causing pain. The pain is accompanied by a cold feeling in the stomach, and the symptoms of dehydration are relieved. The main cause is poor eating habits such as intemperance, often eating cold drinks or cold ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P1/04A61K35/62
Inventor 王明刚任莉陈阳生
Owner CP PHARMA QINGDAO CO LTD
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