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Plant-virus-resisting composition containing glycyrrhizin and ursolic acid and application thereof

An anti-plant virus, ursolic acid technology, applied in applications, plant growth regulators, botanical equipment and methods, etc., can solve problems such as no reports of ursolic acid against plant viruses, and achieve suitable promotion and use, environmental protection. Good compatibility and significant anti-plant virus activity

Inactive Publication Date: 2013-05-29
HARMLESS PESTICIDE RES & SERVICE CENT XIBEI AGRI FORESTRY SCIEN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

According to literature reports, ursolic acid has various biological effects and health functions such as anti-tumor, antibacterial and anti-inflammatory, anti-hyperlipidemia, anti-oxidation, anti-diabetes, anti-virus and immune regulation, etc. Concern, a lot of research has been done on its anti-tumor activity and mechanism of action, but there is no report on the anti-plant virus of ursolic acid in the literature

Method used

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  • Plant-virus-resisting composition containing glycyrrhizin and ursolic acid and application thereof
  • Plant-virus-resisting composition containing glycyrrhizin and ursolic acid and application thereof
  • Plant-virus-resisting composition containing glycyrrhizin and ursolic acid and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Example 1: Preparation of 5% glycyrrhizin · ursolic acid (4:1) emulsifiable concentrate

[0040] At 20-25°C, mix 4 parts of liquiritigenin and 1 part of ursolic acid, add 25 parts of dimethyl sulfoxide, 15 parts of methanol and 5 parts of oil-soluble azone and stir to fully dissolve it, then add it to the above mixture Add 10 parts of OP-10 and butyl acetate successively to make up 100 parts, and stir at a stirring speed of 80-120 rpm for 30-60 minutes to prepare 5% glycyrrhizin-ursolic acid emulsifiable cream.

Embodiment 2

[0041] Example 2: Preparation of 4.5% Liquiritigenin Ursolic Acid (4:0.5) Soluble Liquid

[0042] At 20-25°C, mix 4 parts of liquiritigenin and 0.5 parts of ursolic acid, add 30 parts of dimethyl sulfoxide, 10 parts of methanol and 5 parts of cyclohexanone and stir to fully dissolve them, and then add them to the above mixture in sequence Add 10 parts of 600#, wood vinegar to make up 100 parts, and stir at a stirring speed of 80-120 rpm for 30-60 minutes to prepare a 5% glycyrrhizin-ursolic acid soluble liquid.

Embodiment 3

[0043] Example 3: Preparation of 2.5% Liquiritigen Ursolic Acid (2:0.5) Microemulsion

[0044] At 20-25°C, mix 2 parts of liquiritigenin and 0.5 part of ursolic acid, add 30 parts of methanol and stir to dissolve it fully, then add 15 parts of OP-10 to the above mixture in turn, and the balance is water to stir Stir at a speed of 80-120 rpm for 60-90 minutes to prepare a 2.5% glycyrrhizin-ursolic acid microemulsion.

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Abstract

The invention discloses a plant-virus-resisting agent composition containing glycyrrhizin and ursolic acid and application thereof. Active components of the composition include glycyrrhizin and ursolic acid of which the weight percents are respectively 0.1-10% and 0.1-5%; and the active components can be matched with assistants and other auxiliaries to prepare emulsifiable oil, microemulsion, soluble liquid or water. The virus-resisting composition agent can be used for controlling tobacco mosaic virus (TMV) diseases and other multiple plant virus diseases on tobaccos, chilies, tomatoes, vegetable marrows, potatoes and other crops. The plant-virus-resisting agent composition is safe to the environment, humans, livestock, natural enemies of pests and other beneficial organisms. The preparation process of the plant-virus-resisting agent is simple, low in cost and suitable for popularization.

Description

technical field [0001] The invention relates to a pesticide preparation and a preparation method thereof. In particular, it relates to an anti-plant virus composition containing glycyrrhizin and ursolic acid and its application. Background technique [0002] Plant virus is an intracellular parasitic pathogen composed of nucleic acid and protein with infectious activity. According to the eighth report of the International Committee on Taxonomy of Viruses (ICTV), there are currently 1122 plant virus species found in the world. Plant diseases caused by plant viruses are known as "plant cancers". The annual economic loss caused by plant viruses worldwide is about 60 billion US dollars, and the damage caused by tobacco mosaic virus (TMV) alone exceeds 100 million US dollars. [0003] Since plant viruses are absolutely parasitic to plant cells, the material and energy sites required for virus replication are completely provided by the host plant, resulting in the integration of ...

Claims

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Application Information

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IPC IPC(8): A01N43/16A01N37/36A01P1/00
Inventor 马志卿冯俊涛韩立荣王智辉张兴
Owner HARMLESS PESTICIDE RES & SERVICE CENT XIBEI AGRI FORESTRY SCIEN