Two-dimensional digital micro-fluidic chip based on one-way liquid drop transport
A microfluidic chip and dimensional digital technology, which is applied in laboratory containers, laboratory utensils, chemical instruments and methods, etc., can solve the problems of complex control, easy breakdown and difficult optical detection, and achieve a simplified control signal. , the effect of improving the driving ability
Inactive Publication Date: 2015-01-07
FUDAN UNIV
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Problems solved by technology
However, there are currently two types of chip structures for digital microfluidic chips based on the strip electrode structure. One is that two sets of strip electrodes are placed on the lower plate of the chip, which makes the chip difficult to manufacture, complicated to control, and has problems such as easy breakdown; The second is that two sets of strip electrodes are respectively placed on the upper and lower plates. Although this can be effectively controlled, the dual-plane chip with driving electrodes on the upper plate is not easy to integrate with optical detection and other functions, which limits the application range of the chip.
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[0030] The two-dimensional digital microfluidic chip based on the unidirectional transport of droplets provided by the present invention is not limited to a specific structural configuration, but is preferably a two-dimensional chip structure with a single plane on a single plate. It should be noted that this embodiment is provided for illustrative purposes and is not intended to limit the scope of the present invention in any way.
[0031] A two-dimensional digital microfluidic chip structure based on the unidirectional transport of droplets based on the present invention is as follows: figure 1 , figure 2 As shown, on the substrate 100 is the “moon eclipse” driving electrode of the present invention. It should be noted that the material used as the substrate is not fixed, as long as it is insulated, such as quartz, glass, insulating silicon wafers, etc.; and the electrodes (including the ground electrode described below) can be made of any conductive material. The size an...
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The invention belongs to the technical field of digital microfluidics and in particular relates to a two-dimensional digital micro-fluidic chip based on one-way liquid drop transport. According to the chip, a single-plane chessboard-shaped liquid drop control unit is formed due to the moon-shaped one-way liquid drop transport electrode, reasonable electrode arrangement and simple control signal configuration, and M*N control units (N can be infinitely great) can be controlled by using 2*M control signals, so that two-dimensional liquid drop drive is realized. The provided digital micro-fluidic chip has the advantages of novel and simple control mode, simple manufacturing process, high driving capacity, high batch processing degree, high throughput operation and the like, the defects of the traditional digital micro-fluidic chip are overcome, and the application functions and application range of the digital micro-fluidic chip are greatly widened.
Description
technical field [0001] The invention belongs to the technical field of digital microfluidics, and in particular relates to a two-dimensional digital microfluidics chip based on one-way transport of liquid droplets. Background technique [0002] Digital microfluidic chip refers to a miniaturized chip that operates on discrete droplets, and is an important part of the automated control of the laboratory on a chip (LOC). The digital microfluidic chip based on the electrowetting effect on the medium mainly includes the driving and grounding electrodes, the dielectric layer, the hydrophobic layer and other parts, and uses the voltage signal to control the droplet, so it has the advantages of simple driving method, strong driving force, and easy control. It has many advantages such as convenience and high degree of automation, and has very good development prospects in the field of LOC. [0003] For the digital microfluidic chip, its batch processing and high throughput are its i...
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IPC IPC(8): B01L3/00
Inventor 陈建锋余玉华李嘉周嘉
Owner FUDAN UNIV