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Large and small droplet control based digital micro-fluidic chip

A digital microfluidic and chip technology, applied to laboratory containers, laboratory utensils, chemical instruments and methods, etc., can solve the problems of unrealized splitting of droplets of different sizes and screening of droplets of different sizes, and achieve simple, The effect of simplifying the drive control signal and broadening the application range

Inactive Publication Date: 2013-06-26
FUDAN UNIV
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Problems solved by technology

However, this universal electrode structure only solves the general driving problem of droplets of different sizes, and has not yet realized the generation and splitting of droplets of different sizes, especially the screening of droplets of different sizes, and these are the practical applications of digital microfluidic chips. very important function

Method used

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  • Large and small droplet control based digital micro-fluidic chip
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  • Large and small droplet control based digital micro-fluidic chip

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Embodiment Construction

[0034] The present invention provides a digital microfluidic chip based on large and small droplet manipulation based on the chip structure and driving method of the current electrowetting digital microfluidic technology on a medium. It should be noted that this embodiment is provided for illustrative purposes and is not intended to limit the scope of the present invention in any way.

[0035] According to the present invention, a digital microfluidic chip based on the control of large and small droplets shows a schematic cross-sectional view of two chips at 90 degrees to each other. figure 1 , figure 2 As shown, there are first electrode layers E1 - E10 on the first insulating substrate 100 . It should be noted that the material used as the substrate is not fixed, as long as it is insulated, such as quartz, glass, insulating silicon wafers, etc.; and the electrodes can be made of any conductive material, the size and spacing of the electrodes and the individual characterist...

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Abstract

The invention belongs to the technical field of digital micro-fluidics, concretely relates to a medium electro-wetting driving based digital micro-fluidic technology, and more specially relates to a large and small droplet control based digital micro-fluidic chip. A general electrode structure which is treated as a base is combined with a bar-shaped rectangular electrode, a double-electrode-plate chip structure is formed through reasonable configuration, and a capacitor is arranged for sensing in order to generate, transport, split, mix, screen droplets having different sizes. The large and small droplet control based digital micro-fluidic chip has the advantages of novelty, simplicity, strong integrateability, high automation degree and the like, widely widens the utility functions and the application range of electro-wetting digital micro-fluidic chips.

Description

technical field [0001] The invention belongs to the technical field of digital microfluidics, and in particular relates to a digital microfluidic chip based on the manipulation of large and small droplets based on the electrowetting digital microfluidic technology on a medium. Background technique [0002] Digital microfluidic technology refers to the technology of manipulating a single droplet through various driving methods such as light, heat, voltage, and surface acoustic waves to complete functions such as sampling, mixing, transport, and detection of microfluidic droplets. The digital microfluidic technology based on electrowetting on the medium refers to that on a chip containing an insulating medium, the contact angle of the droplet on the medium can be changed by applying a voltage signal, so that the droplet undergoes asymmetric deformation, thereby generating internal force to A technology to achieve droplet manipulation. This technology is attracting more and mo...

Claims

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Application Information

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IPC IPC(8): B01L3/00
Inventor 陈建锋余玉华周嘉
Owner FUDAN UNIV
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