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Targeting antitumor and anticancer medicine and its preparation method

An anti-tumor and targeted technology, used in anti-tumor drugs, pharmaceutical formulations, drug combinations, etc., can solve problems such as large toxic and side effects, no obvious breakthrough in treatment, and poor efficacy, and achieve normal cardiac contraction and skin circulation. The effect of prosperous and immune function enhancement

Active Publication Date: 2013-07-10
何忠琳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, to this day, cancer is still a worldwide problem. Countries around the world are exploring, researching and developing anti-cancer drugs. Every year, many new anti-cancer drugs come out, but these drugs generally have poor curative effect and severe side effects. A variety of problems, there is still no obvious breakthrough in treatment

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  • Targeting antitumor and anticancer medicine and its preparation method
  • Targeting antitumor and anticancer medicine and its preparation method

Examples

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Effect test

Embodiment 1

[0095] A targeted anti-tumor and anti-cancer drug, the components of which contain (weight %) 57 kg of pseudo-black spiny ant, 28.5 kg of placenta, 14.3 kg of red Qi, 0.13 kg of cordycepin, and 0.07 kg of corydalis.

[0096] The following describes the extraction and preparation methods of each single drug of the present invention as follows:

[0097] Pseudo-black spiny ant: In spring, summer, and autumn, excavate wild life at an altitude of more than 3,500 meters in the west, wash it → raise it in pure water biotechnology and let it die after 7 days → dry it in the sun or dry at 60°C for 7 hours → store in the refrigerator for later use → Take 57kg pseudo-black spiny ant from the refrigerator → crush → screen dry powder through 24 mesh → place the dry powder in the CO extractor → adjust the extraction solvent flow rate 15L / h → extraction pressure 30MPa → temperature 60℃ for 3h → collect and extract Separation of petroleum ether at 80°C→collect the separated liquid and heat it to 1...

example 1

[0105] The present invention is suitable for various types of clinics in various stages, such as patients who are unwilling to undergo surgery, patients who have lost the opportunity of surgery, and patients after surgery, as well as the treatment of early, middle and late cancers. Especially: lung cancer, liver cancer, breast cancer, esophageal cancer, urinary system tumors, gynecological tumors, etc. are very effective. Example 1: Xie, male, 66 years old, a patient with liver cancer. In 2005, he felt unwell and went to Beijing 301 General Hospital of the People’s Liberation Army for a CT examination. The report showed that irregular masses of increased radioactive uptake were seen in the liver, and the maximum SUV was 16.81. , The average is 7.56, the maximum delayed imaging SUV is 16.52, the average is 7.65, the radioactive uptake is uneven, and the center is an undead zone with radioactive defect; the uneven density of the corresponding part of the same CT scan is reduced, a...

Embodiment 2

[0110] The targeted anti-tumor and anti-cancer medicament of this embodiment is prepared by using black spiny ant, placenta, red sage, cordycepin, and corydalis as raw materials, and its components (weight %) are black spiny ant 57.8 kg and placenta 28 kg , Red Qi 14kg, Cordycepin 0.13kg, Corydalis 0.07kg;

[0111] First, the refined extraction of the raw material single drug and its related technical methods are as follows:

[0112] ①Pseudo-black spiny ant: In spring, summer, and autumn, explore and dig wild living organisms above 3500 meters above sea level in the western part of the country, wash them → raise them in pure water biotechnology and let them die after 7 days → dry in the sun or dry at 60℃ for 7 hours → store in the refrigerator for later use → Take 57.8 kg of pseudo-black spiny ants from the refrigerator → crush → screen the dry powder through 24 mesh → place the dry powder in the CO extractor → adjust the flow rate of the extraction solvent 15L / h → extraction press...

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Abstract

The invention relates to a targeting antitumor and anticancer medicine. A preparation method of the medicine comprises the following steps: mixing prepared Polyrhachis Vicina Roger, prepared placenta, Radix Hedysari, cordycepin and Rhizoma Corydalis, injecting second-grade medicinal distilled water to the obtained mixture to prepare a liquid, placing the liquid in a container, adding active carbon for processing, filtering, adding to injection water and a container containing a sodium chloride solution for diluting, and uniformly stirring; adjusting the osmotic pressure of the injection water by sodium hydroxide, and filtering by a filter to obtain a filtrate according with the production requirement of a Chinese GMP standard reached large transfusion enterprise; and filling to a 250ml or 500ml glass bottle, and disinfecting under a pressure of 0.39MPa at a temperature of 116DEG C to obtain the targeting antitumor and anticancer medicine. The medicine has the advantages of safety, non-toxicity, no side effects, performance of the wide-spectrum antitumor, anticancer and anti-injection effects, containment of abundant nutritional components, participation of the immune function adjustment, and improvement of the generation level and the acceptor expression level of interleukin-2 (1L-2).

Description

Technical field [0001] The invention relates to a traditional Chinese medicine preparation method and chemical medicament without taboos that are routinely used in the "National Pharmacopoeia", specifically, a new type of integrated targeted anti-tumor and anti-cancer medicament and a preparation method thereof. Background technique [0002] Cancer is still one of the most important diseases threatening human health. It takes the lives of thousands of patients every year. At present, air pollution, environmental pollution, and cancer patients are increasing year by year. As early as the 1950s and 70s, the United States invested a lot of resources and manpower, determined to overcome cancer by the end of the last century. However, cancer is still a worldwide problem. Countries all over the world are exploring the research and development of anti-cancer drugs. Every year, a variety of new anti-cancer drugs come out, but these drugs generally have poor efficacy and high toxic side e...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/66A61P35/00A61K31/7076A61K35/64A61K35/50
Inventor 何忠琳
Owner 何忠琳
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