Raman signal detecting and analyzing system and method

A Raman signal and optical signal technology, which is applied in the field of measuring instruments, can solve problems such as unacceptable costs, and achieve the effects of improving light transmission efficiency, stabilizing the ratio, and reducing costs

Active Publication Date: 2013-07-10
HONG KONG APPLIED SCI & TECH RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the cost of these new designs is unacceptable when used in the home to monitor physiological parameters

Method used

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  • Raman signal detecting and analyzing system and method
  • Raman signal detecting and analyzing system and method
  • Raman signal detecting and analyzing system and method

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Embodiment Construction

[0018] As used herein and in the claims, "comprising" means including the following elements but not excluding others.

[0019] Referring to Fig. 1, Fig. 1 shows the device of the present invention in the post-filtered transmission mode.

[0020] The transmission mode system generally includes an excitation light source 28 , a laser line filter 30 , a collimating lens 32 , an optical module 42 , a detector 24 , a signal processing unit 40 , a microprocessor 26 and a computer readable storage medium 44 . The detector 24 is connected to a signal processing unit 40 which is in turn connected to a microprocessor 26 . Computer readable storage media 44 is connected to microprocessor 26 .

[0021] The excitation light source 28 is used to emit at least one excitation wavelength λ E The excitation light passes through one or two laser line filters 30 and reaches the sample 20 to be measured. Due to the excitation light, an optical signal, in particular a Raman signal, is emitted f...

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Abstract

The invention discloses a Raman signal detecting and analyzing system and method. The method comprises the following steps of: sending exciting light to a sample so as to generate a Raman signal; modulating the Raman signal through a plurality of optical filters and modulators, wherein the modulated Raman signal comprises two orthogonal components; calculating the intensity of the two components according to the first harmonic wave of the modulated Raman signal; and then determining the content of a specified analyte in the sample according to the ratio of the intensity of the two components.

Description

【Technical field】 [0001] The invention relates to a measuring instrument, in particular to a measuring instrument for detecting the content of an analyte in a sample by using an internal standard method to analyze a Raman signal. 【Background technique】 [0002] Raman spectroscopy is a powerful tool for quantifying the composition and concentration of an analyte within a sample. In physiological sensing applications, such optical measurements are usually performed in the near-infrared region. The Raman signal is usually very weak, for example, the ratio of Raman signal intensity to excitation signal intensity is less than 10 -10 . Furthermore, Raman signals are ultrasensitive to measurement conditions, such as laser fluctuations, optical brightening, temperature changes, changes in sample size and shape, and optical alignment. Therefore, the internal standard method is usually used during Raman signal analysis. The basic principle of the internal standard method is to sim...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/65G01N21/01
Inventor 郭嘉祥张春朱聿熹梁立慧
Owner HONG KONG APPLIED SCI & TECH RES INST
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