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Novel catgut implantation at acupoint and preparation method thereof

A acupuncture point and a new type of technology, applied in rayon manufacturing, medical science, conjugated rayon, etc., can solve problems that affect human health, complex synthesis steps, and inability to exert medicinal value, and achieve good degradability and biophase Capacitance, avoid pain bulge, avoid rejection and infection

Active Publication Date: 2015-01-21
宁波贝昂生物材料有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The Chinese patent publication number is CN1748802A, the publication date is March 22, 2006, and the title of the invention is: the invention of the application of degradable material suture in acupoint implantation. The synthetic materials provided are polyglycolic acid, glycolide and lactide. Ester copolymers, dioxanone polymers, sugar-acid polymers and other high-molecular synthetic materials such as surgical sutures have the advantages of absorbing and stabilizing tissue reactions, but the materials synthesized by this method have a single effect and have no other medicinal uses. ingredients, can not exert more medicinal value
In addition, the synthesis steps are complicated, and the prepared products often contain small molecule residues, which affect human health.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0025] The preparation method of the acupoint embedding thread comprises the following steps:

[0026] a Preparation of spinning solution

[0027] Soak the sugar-containing Chinese herbal medicine in 50-100°C distilled water, let it stand for 2-10 hours, filter the residue with gauze, collect the polysaccharide filtrate, concentrate the polysaccharide filtrate in an environment of 50-100°C, and obtain the mass fraction concentration It is a 5%~25% polysaccharide concentrate. At the same time, mix the polysaccharide extracts of western medicine and Chinese herbal medicine in a mass ratio of 0:100~5:95, dissolve in water, stir well, and disperse evenly. The vacuum degree is -0.05 Degassing in ~-0.5Mpa environment for 0.5~3h to get spinning solution;

[0028] b Filament preparation

[0029] Add the spinning solution obtained through step a into the spinning machine, extrude it at a speed of 5-60ml / min by a metering pump, and solidify and form it in an absolute ethanol coagulati...

Embodiment 1

[0035] a Raw material extraction

[0036] Soak the stems of Bletilla striata rich in polysaccharides in distilled water at 50°C, and let stand for 10 hours. After the polysaccharides are fully dissolved, filter the residue with 4 layers of gauze, collect the polysaccharide filtrate, and place the polysaccharide filtrate in a 50°C environment Concentrating to obtain a polysaccharide concentrate with a mass fraction concentration of 10%, degassing for 3 hours in an environment with a vacuum of -0.1Mpa to obtain a spinning solution;

[0037] b Filament preparation

[0038] Add the spinning solution obtained in step a into the spinning machine, and extrude it at a speed of 5ml / min by a metering pump. Dried in the oven of C, winding obtains the primary growth silk that diameter is 2mm;

[0039] c Cutting and packaging of acupoint implantation thread

[0040] Cut the primary growth filaments obtained in step b into 0.5 cm long implanted wires, disinfect and sterilize them with me...

Embodiment 2

[0042] a Raw material extraction

[0043]Soak the Radix Astragali rich in polysaccharide components in 80°C distilled water, let it stand for 8 hours, wait for the polysaccharide components to fully dissolve, filter the residue with 5 layers of gauze, collect the polysaccharide filtrate, place the polysaccharide filtrate in an environment of 80°C to concentrate, Obtain a polysaccharide concentrate with a mass fraction concentration of 20%. At the same time, aspirin with medicinal efficacy is added to the polysaccharide concentrate. The mass ratio of western medicine and Astragalus polysaccharide extract is 1:99. Fully stir and mix evenly. Spinning solution was obtained after degassing in the environment of -0.2Mpa for 2 hours;

[0044] b Filament preparation

[0045] Add the spinning solution obtained through step a into the spinning machine, and extrude it at a speed of 20ml / min by a metering pump. Dried in the environment of ℃, coiling obtains the primary growth silk that ...

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Abstract

The invention relates to novel catgut implantation at acupoint and a preparation method thereof, which belong to the technical field of textile engineering. The novel catgut implantation at acupoint is prepared by the following steps of: extracting natural macromolecular polysaccharide from Chinese herbal medicines rich in polysaccharide components, dissolving the macromolecular polysaccharide in a solvent to prepare a spinning solution, adding Western medicine components for spinning to obtain the catgut implantation with the diameter of 0.5mm-2mm and the length of 0.2cm-5cm, and sterilizing and packaging the catgut implantation. The prepared catgut implantation is easily degraded and absorbed in a human body and has high biocompatibility, the process is simple, the cost is low, and harmful substances are not generated.

Description

technical field [0001] The invention relates to a novel acupuncture point embedding thread and a preparation method thereof, belonging to the technical field of textile engineering. Background technique [0002] Acupoint catgut embedding therapy is to stimulate meridians, balance yin and yang, reconcile qi and blood, and adjust viscera through needles and implanted threads in acupoints to achieve the purpose of treating diseases. The implanted thread usually uses sheep catgut or other absorbable medical sutures. The sheep catgut is made of the submucosa of the small intestine of the sheep. The main medical mechanism of the most widely used common medical suture catgut at present is to replace the physical stimulation of acupuncture. The therapy is relatively simple and has no other extended curative effect. In response to the above problems, a large number of drug lines have been designed and applied. The main preparation method is to immerse medical catgut in different me...

Claims

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Application Information

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IPC IPC(8): A61L31/04A61L31/16D01F9/00D01F8/18D01F1/02
Inventor 杨红军向艳丽皮玉萍徐卫林叶青
Owner 宁波贝昂生物材料有限公司
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