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Application of traditional Chinese medicine composition to preparation of medicament for treating influenza B virus

A kind of influenza B, composition technology, applied in the direction of hydroxyl compound active ingredients, pharmaceutical formulations, plant raw materials, etc., can solve problems such as unmentioned effects and the like

Inactive Publication Date: 2013-12-18
BEIJING YILING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Chinese patent 03143211.5 discloses that the Chinese medicine composition has an antiviral effect and can be applied to influenza, but the patent does not mention the effect of the Chinese medicine composition on influenza B

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0111] The raw material formula is :

[0112] 255g forsythia, 255g honeysuckle, 255g isatidis, 51g rhubarb, 85g patchouli, 255g Mianmaguanzhong, 85g rhodiola, 7.5g menthol, 85g honey ephedra, 85g fried bitter almonds, 255g houttuynia, 85g licorice , gypsum 255g;

[0113] The preparation method is :

[0114] (1) Weigh Chinese herbal medicines according to the above prescription, select them cleanly, and break them into pieces as appropriate;

[0115] (2) Patchouli is broken, add 6 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0116] (3) Forsythia, Ephedra, Houttuynia cordata, and rhubarb, extract twice with 8 times the amount of 70% ethanol, the first time for 2 hours, and the second time for 1.5 hours, the extracts are combined and filtered, the ethanol is recovered, and the filtrate is used for la...

Embodiment 2

[0121] The raw material drug formula is:

[0122] 300g forsythia, 200g honeysuckle, 300g isatidis, 40g rhubarb, 100g patchouli, 200g rhodiola, 60g rhodiola, 5g menthol, 100g ephedra, 60g bitter almond, 300g houttuynia, 60g licorice, gypsum 300g ;

[0123] The preparation method is :

[0124] (1) Weigh Chinese herbal medicines according to the above prescription, select them cleanly, and break them into pieces as appropriate;

[0125] (2) Patchouli is broken, add 5 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0126] (3) Forsythia, Ephedra, Houttuynia cordata, and rhubarb, extract twice with 6 times the amount of 50% ethanol, the first time for 3 hours, and the second time for 1 hour, the extracts are combined and filtered, the ethanol is recovered, and the filtrate is used for later use;

[0127] ...

Embodiment 3

[0131] The raw material drug formula is:

[0132] 200g forsythia, 300g honeysuckle, 200g isatidis, 60g rhubarb, 60g patchouli, 300g Mianmaguanzhong, 60g rhodiola, 9g menthol, 60g ephedra, 100g bitter almond, 200g houttuynia, 100g licorice, gypsum 200g ;

[0133] The preparation method is :

[0134] (1) Weigh Chinese herbal medicines according to the above prescription, select them cleanly, and break them into pieces as appropriate;

[0135] (2) Patchouli is broken, add 10 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0136] (3) Forsythia, Ephedra, Houttuynia cordata, and rhubarb, extract twice with 10 times the amount of 90% ethanol, the first time for 1 hour, and the second time for 3 hours, the extracts are combined and filtered, the ethanol is recovered, and the filtrate is used for later use; ...

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PUM

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Abstract

The invention discloses application of a traditional Chinese medicine composition to preparation of medicaments for treating influenza B virus. The traditional Chinese medicine composition comprises medicines of fructus forsythia, ephedra stem and bitter apricot kernel, and is proved to be capable of confronting influenza B virus effectively; and the traditional Chinese medicine composition has effect on influenza virus substantially better than on other viruses.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition, in particular to the application of a traditional Chinese medicine composition in the preparation of medicines for treating influenza B, which belongs to the field of traditional Chinese medicine applications. Background technique [0002] Influenza B is the common cold caused by influenza B virus, and it is also a highly contagious and fast-spreading disease. It is characterized by rapid onset, chills, fever, body temperature rises to a peak within a few hours to 24 hours, and gastrointestinal symptoms are more common than other types of influenza. It is mainly spread through droplets in the air, person-to-person contact or contact with contaminated items. It is mainly popular in winter and spring, and can cause local outbreaks. [0003] Tamiflu has long been thought to have similar efficacy against influenza A and B. The researchers pointed out that test tube...

Claims

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Application Information

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IPC IPC(8): A61K36/78A61P31/16A61K33/06A61K31/045
Inventor 张会欣王宏涛秦拢李向军
Owner BEIJING YILING PHARMA
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