Bioaerosol monitoring and early-warning method

A biological aerosol, monitoring and early warning technology, applied in the direction of analysis materials, instruments, etc., to achieve the effect of easy production, low cost, and suppression of interference

Inactive Publication Date: 2014-03-12
INST OF ELECTRONICS CHINESE ACAD OF SCI +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] At present, the existing technology lacks methods for on-site monitoring and early warning of toxic bioaerosols, especially low-concentration toxic bioaerosols

Method used

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Examples

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Embodiment 1

[0031] In an exemplary embodiment of the present invention, a bioaerosol monitoring and early warning method based on a surface plasmon resonance sensor is proposed. figure 1 It is a schematic structural diagram of a surface plasmon resonance sensor used in a bioaerosol monitoring and early warning method according to the embodiment of the present invention.

[0032] Such as figure 1 As shown, the surface plasmon resonance sensor includes: a light source 10 , a sensitive chip 20 , a light detector 30 , and a sample cell 40 . Wherein, the sensitive chip 20 is made up of a glass prism 21a and a glass substrate 21b that is closely attached to the bottom surface of the glass prism by a coupling liquid, and the other side of the glass substrate opposite to the bonding surface is covered with a few nanometer thick chromium film or a titanium film (in the figure not shown), and tens of nanometers thick gold film 21c. The glass prism 21a is a hemispherical glass prism, a semi-cylind...

Embodiment 2

[0045] In another exemplary embodiment of the present invention, a method for monitoring and early warning of bioaerosol based on an optical waveguide interferometer sensor is proposed. The sensitive chip of the optical waveguide evanescent wave sensor is composed of one or more of planar optical waveguide, three-dimensional optical waveguide, and optical fiber.

[0046] Please refer to Figure 4 , the optical waveguide evanescent wave sensor, including: a light source 10, a sensitive chip 20, a light detector 30, and a sample cell 40. The sensitive chip 20 of the optical waveguide evanescent wave sensor includes a potassium ion-exchanged glass waveguide layer 22b formed on a glass substrate 22a and a high refractive index gradient film 22c deposited on a partial surface of the potassium ion-exchanged glass optical waveguide; The surface is the surface of the high refractive index gradient film. The sample cell 40 is tightly covered on the sensitive chip 20, and is bent to c...

Embodiment 3

[0064] In the third exemplary embodiment of the present invention, a bioaerosol monitoring and early warning method based on a quartz crystal microbalance sensor is proposed. Figure 8 It is a schematic diagram of the structure of the quartz crystal microbalance sensor in the embodiment of the present invention.

[0065] Please refer to Figure 8 , the quartz crystal microbalance sensor comprises: a sensitive chip 20 made of a quartz wafer, gold film or silver film electrodes 23a are deposited on both sides of the quartz wafer, and the sensitive surface of the sensitive chip is a gold film or silver film electrode The surface of the bearing 23b, through two metal brackets (23c, 23d) in the part of the sample cell 40 to support the quartz wafer, the two electrodes 23a are electrically connected to the signal detection and early warning module 50 through the two metal brackets (23c, 23d). Both the sensitive chip 20 and the support 23b are placed in the sample cell 40;

[0066]...

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Abstract

The invention provides a bioaerosol monitoring and early-warning method. The bioaerosol monitoring and early-warning method comprises the following steps: subjecting a bioaerosol to filtration so as to convert the bioaerosol into an aqueous solution sample; and then detecting biological particles non-specifically adsorbed on the sensitive surface of a sensor from the aqueous solution sample in real time by using the sensor which is sensitive to surface mass change. With the method, monitoring and early warning of the bioaerosol are realized, and bases are provided for subsequent identity detection and protection of the biological particles; and the method has wide application prospects.

Description

technical field [0001] The invention belongs to the technical field of biological detection, and relates to the filtration and solubilization technology of biological aerosol, the non-specific adsorption and enrichment technology of biological particles, the surface plasmon resonance sensing technology, and the optical waveguide sensing technology, in particular to a biological aerosol monitoring Early warning method. Background technique [0002] Bioaerosol refers to the suspension system of all gas-solid and gas-liquid mixture particles containing biological particles in the air. Toxic bioaerosols are called toxic bioaerosols if they contain bacteria, viruses and disease-causing microorganisms such as allergenic pollen, mold spores, fern spores and parasite eggs. In addition to the characteristics of general aerosols, toxic bioaerosols also have the characteristics of infectiousness, lethality, injury and sensitization. In addition to existing in the battlefield environme...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N15/00
Inventor 祁志美逯丹凤赵湛杜利东童朝阳
Owner INST OF ELECTRONICS CHINESE ACAD OF SCI
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