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External traditional Chinese medicinal preparation for treating acne rosacea and preparation method thereof

A technology of traditional Chinese medicine preparation and rosacea, which is applied in the field of traditional Chinese medicine preparation for treating rosacea and its preparation, can solve the problems of unsatisfactory effects, and achieve the effects of strengthening heat-clearing and detoxification, enhancing therapeutic effect, and good therapeutic effect

Inactive Publication Date: 2014-04-16
钟山县同古镇卫生院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinically, there is no shortage of still using certain traditional Chinese medicines to treat skin diseases, but the effect is not satisfactory.

Method used

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  • External traditional Chinese medicinal preparation for treating acne rosacea and preparation method thereof
  • External traditional Chinese medicinal preparation for treating acne rosacea and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0042] Preparation method of the present invention:

[0043] The preparation method of facial mask agent of the present invention is: take Burnet 1000g, Senecio 1000g, Sapinberry 1000g, Patrinia 1000g, Scutellaria baicalensis 1000g, Angelica dahurica 1000g, Atractylodes atractylodes 1000g, Salvia miltiorrhiza 1000g, Radix radix 1000g, Sophora flavescens 1000g, Radix 1000g. 1000g, Phellodendron 1000g, Fructus Cnidii 1000g, Cortex Morus alba 1000g, Honeysuckle 1000g, Peppermint 1000g; first crush the raw material into coarse powder, then further pulverize, pass through a 100-120 mesh sieve, so that the amount of fine powder that can pass through the sieve is to 30%, collect the fine powder that passes through the sieve to obtain fine powder a; then put the coarse powder that cannot pass through the 120 mesh sieve into a multi-functional extraction tank for extraction twice, add 10 times the amount of water for decoction for 1 hour for the first time, and decoct for 1 hour for the...

Embodiment 3

[0069] Embodiment 3: Vaginal mucosa irritation test result

[0070] 1. Test method:

[0071] After 3 days of experimental animal quarantine, select 18 above-mentioned healthy rabbits for use, and be randomly divided into three groups, each group of 6, respectively: blank control, excipient control, group of the present invention (facial mask agent) (5 times by application liquid) concentration). Sterilized tampons of appropriate size soaked in sterilized physiological saline and the test substance were placed in the vagina of the animals in the vehicle control group and the test substance group, and were in contact with the vaginal mucosa for 6 hours, and the animals were sacrificed 24 hours later. The local vaginal tissue was taken out and the lesion was observed.

[0072] 2. Test results: vaginal mucosa irritation test results

[0073]

[0074]

Embodiment 4

[0075] Embodiment 4: skin allergy test result

[0076] Taking the gel of the present invention as an example, the induction and stimulation contact tests were carried out, and the test mice were observed after 24 hours and 48 hours, and there was no phenomenon such as erythema and edema in the skin, and there was no difference with the negative control group. The results show that the gel has close to zero skin reaction intensity, that is, no skin allergy.

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Abstract

The invention provides an external traditional Chinese medicinal preparation for treating acne rosacea. The preparation is prepared from the following bulk drugs in parts by weight: 10-20 parts of garden burnet, 10-20 parts of climbing groundsel herb, 10-20 parts of sapindus, 10-20 parts of dahurian patrinia herb, 10-20 parts of scutellaria baicalensis, 10-20 parts of angelica root, 10-20 parts of rhizoma atractylodis, 10-20 parts of salviae miltiorrhizae, 10-20 parts of rhizoma bletillae, 10-20 parts of sophora flavescens, 10-20 parts of stemona, 10-20 parts of cortex phellodendri, 10-20 parts of fructus cnidii, 10-20 parts of cortex mori radicis, 10-20 parts of honeysuckle, and 10-20 parts of mint. The external traditional Chinese medicinal preparation can directly reach the focus, is applied for clearing heat to remove stasis, can be directly contacted with the focus to strengthen the effects of clearing heat and removing toxicity, activating blood circulation to remove stasis, and promoting skin lesion to quickly heal or resolve, can be used for improving the permeability of blood capillaries to achieve the effects of clearing heat and drying dampness, nourishing and activating blood, dispelling wind and arresting itching, so that medicinal components for dispelling wind and killing bacteria, promoting pus discharge and tissue regeneration can infiltrate into a body in a transcutaneous manner, so that the treatment effect can be strengthened, and the curative effect can be improved.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicinal preparation for treating rosacea and a preparation method thereof. Background technique [0002] Rosacea, also known as rosacea (rosacea), is more common in middle-aged people aged 30-50, more women than men, but severe cases are generally seen in men. It is a chronic inflammatory disease that occurs in the middle of the face. The exact cause of rosacea is unclear, and many factors may induce or aggravate the disease, including local vasomotor nerve disorders, hair follicles and local repeated infections, use of spicy food, drinking, hot and cold stimulation, mental stress, emotional agitation, Endocrine dysfunction, etc. In recent years, the relationship between Helicobacter pylori infection and immune factors and this disease has also begun to attract attention. [0003] The course of the di...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61P17/10
Inventor 不公告发明人
Owner 钟山县同古镇卫生院
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