External traditional Chinese medicinal preparation for treating acne rosacea and preparation method thereof
A technology of traditional Chinese medicine preparation and rosacea, which is applied in the field of traditional Chinese medicine preparation for treating rosacea and its preparation, can solve the problems of unsatisfactory effects, and achieve the effects of strengthening heat-clearing and detoxification, enhancing therapeutic effect, and good therapeutic effect
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[0042] Preparation method of the present invention:
[0043] The preparation method of facial mask agent of the present invention is: take Burnet 1000g, Senecio 1000g, Sapinberry 1000g, Patrinia 1000g, Scutellaria baicalensis 1000g, Angelica dahurica 1000g, Atractylodes atractylodes 1000g, Salvia miltiorrhiza 1000g, Radix radix 1000g, Sophora flavescens 1000g, Radix 1000g. 1000g, Phellodendron 1000g, Fructus Cnidii 1000g, Cortex Morus alba 1000g, Honeysuckle 1000g, Peppermint 1000g; first crush the raw material into coarse powder, then further pulverize, pass through a 100-120 mesh sieve, so that the amount of fine powder that can pass through the sieve is to 30%, collect the fine powder that passes through the sieve to obtain fine powder a; then put the coarse powder that cannot pass through the 120 mesh sieve into a multi-functional extraction tank for extraction twice, add 10 times the amount of water for decoction for 1 hour for the first time, and decoct for 1 hour for the...
Embodiment 3
[0069] Embodiment 3: Vaginal mucosa irritation test result
[0070] 1. Test method:
[0071] After 3 days of experimental animal quarantine, select 18 above-mentioned healthy rabbits for use, and be randomly divided into three groups, each group of 6, respectively: blank control, excipient control, group of the present invention (facial mask agent) (5 times by application liquid) concentration). Sterilized tampons of appropriate size soaked in sterilized physiological saline and the test substance were placed in the vagina of the animals in the vehicle control group and the test substance group, and were in contact with the vaginal mucosa for 6 hours, and the animals were sacrificed 24 hours later. The local vaginal tissue was taken out and the lesion was observed.
[0072] 2. Test results: vaginal mucosa irritation test results
[0073]
[0074]
Embodiment 4
[0075] Embodiment 4: skin allergy test result
[0076] Taking the gel of the present invention as an example, the induction and stimulation contact tests were carried out, and the test mice were observed after 24 hours and 48 hours, and there was no phenomenon such as erythema and edema in the skin, and there was no difference with the negative control group. The results show that the gel has close to zero skin reaction intensity, that is, no skin allergy.
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