Medicinal composition for treating essential hypertension and application thereof

A technology of essential hypertension and composition, which is applied in the field of medicine, can solve the problems of insufficient attention to the protection and reversal of target organs, achieve the purpose of inhibiting the decrease of eNOS protein expression in vascular tissue, inhibition of increase and decrease of NO, suitable for long-term The effect of taking

Inactive Publication Date: 2014-04-30
XINXIANG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The remaining problems mainly include: ①The antihypertensive mechanism of traditional Chinese medicine is not yet clear; ②The screening of natural active ingredients of antihypertensive Chinese medicine is not yet clear; ③Insufficient attention to target organ protection and reversal

Method used

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  • Medicinal composition for treating essential hypertension and application thereof
  • Medicinal composition for treating essential hypertension and application thereof
  • Medicinal composition for treating essential hypertension and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A pharmaceutical composition for the treatment of essential hypertension, which comprises the following raw materials prepared in parts by weight: Lycium barbarum polysaccharide component-II10 parts, Lycium barbarum polysaccharide component-III10 parts, and unbound terpene-3β- 7 parts of alcohol, 10 parts of Astragalus polysaccharide component Al and 3 parts of Leonurusin A.

Embodiment 2

[0029] A pharmaceutical composition for the treatment of essential hypertension, the pharmaceutical composition comprising the following raw materials formulated in parts by weight: Lycium barbarum polysaccharide component-II 100 parts, Lycium barbarum polysaccharide component-III 100 parts, and uninhibited terpene-3β- 100 parts of alcohol, 100 parts of Astragalus polysaccharide component Al and 100 parts of Leonurusin A.

Embodiment 3

[0031] A pharmaceutical composition for the treatment of essential hypertension, which comprises the following raw materials formulated in parts by weight: Lycium barbarum polysaccharide component-II55 parts, Lycium barbarum polysaccharide component-III55 parts, and uninhibited terpene-3β- 53.5 parts of alcohol, 55 parts of Astragalus polysaccharide component A1 and 51.5 parts of Leonurusin A.

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PUM

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Abstract

The invention belongs to the technical field of medicine, particularly relates to a medicinal composition for treating essential hypertension and application thereof. The medicinal composition is prepared from the following raw materials: Lycium barbarum polysaccharide component II, Lycium barbarum polysaccharide component III, friedelin-3beta-ol, Astragalus polysaccharide component A1 and Ajugol A. The medicinal composition provided by the invention has obvious therapeutic effect of inhibiting clinical symptoms of essential hypertension, has the advantages of stable quality control, no toxicity and is suitable for long-term administration.

Description

Technical field [0001] The invention belongs to the technical field of medicine, and specifically relates to a pharmaceutical composition for treating essential hypertension and its application. Background technique [0002] Essential hypertension is an independent disease with elevated blood pressure as the main clinical manifestation. Hypertension is a common and frequently-occurring disease that endangers human health. It can cause serious damage to important organs such as the heart, brain, and kidneys. According to data provided by the Bureau of Disease Control and Prevention of the Ministry of Health of China, there are about 160 million people in mainland China, while the control rate of people suffering from hypertension is only 6.1%. Modern medicine has not clarified the cause of hypertension, so symptomatic treatment is usually adopted. Almost all the selected drugs have side effects of varying degrees, and there are obvious limitations in treatment. In the treatment ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/715A61P9/12A61K31/7048A61K31/56
Inventor 李鹏侯软玲毕凌云王建刚王亚莉朱利红张群妹黄宁杨静王永霞杨帆朱茉莉赵繁荣马丽娟张玉林
Owner XINXIANG MEDICAL UNIV
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