Paliurus ramosissimus extract with antifungal activity and preparations and applications thereof

A technology of extracting the seeds of vesicles, applied in the field of medicine, can solve the problems of long duration and high recurrence rate of fungal diseases

Active Publication Date: 2014-04-30
四川梓橦宫药业股份有限公司
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  • Abstract
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AI Technical Summary

Problems solved by technology

Mycosis has a long course of disease and a high recurrence rate, requiring patients to take long-term medication

Method used

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Embodiment Construction

[0014] The present invention will be described in detail below in conjunction with specific embodiments. The present invention will be further described in detail below in conjunction with examples, but the embodiments of the present invention are not limited thereto.

[0015] The preparation of embodiment Scutellaria japonica extract

[0016] 1. Preparation of the ethanol extract of S. japonica

[0017] (1) Get 1 kg of the fresh product of the whole plant plant (or any part thereof) of S. japonicus, add 95% (volume concentration) ethanol that is 8 times of the volume of S. sylvestris and soak for 1-2 days, then pulverize the leaves, roots and stems, and then Extract and soak with 12 times the volume of 95% ethanol for 3 days, collect the extract, recover ethanol under reduced pressure, and freeze-dry the concentrated solution to obtain the ethanol extract of fenugreek.

[0018] (2) Get 1 kg of the fresh plant (or any part thereof) of the whole plant of S. japonicus, pulveri...

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PUM

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Abstract

The invention discloses a Paliurus ramosissimus extract with antifungal activity and preparations and applications thereof. The preparation method includes the steps of extracting terpenoids, flavonoids, alkaloids, cumarins (including glycosides and monomers of terpenoids, flavonoids, alkaloids and cumarins) and polysaccharides from a whole plant or any part of Paliurus ramosissimus with solvent, collecting extractive solution, concentrating and drying to obtain Paliurus ramosissimus extract; making into tablets, granules, ointment, gel, film, liniment, lotion and spray. The Paliurus ramosissimus extract with antifungal activity and preparations disclosed by the invention are used for preparing antifungal drugs.

Description

technical field [0001] The present invention relates to the field of medicine, and in particular to an extract of Scutellaria japonicus with antifungal activity and various preparations and applications thereof. Background technique [0002] Along with the increase of population, the aggravation of environmental pollution, various diseases caused by fungi, such as various onychomycosis, psoriasis etc., have become the frequently-occurring diseases of mankind. The incidence of such diseases is high. According to statistics, the incidence of fungal diseases in my country is as high as 78%. Mycosis is divided into superficial mycoses and deep mycoses. Superficial fungal infection, also known as dermatophytosis, is a stubborn and refractory chronic skin disease with a high reinfection rate, accounting for more than 80% of the total incidence of fungal diseases; Mucous membranes and viscera are mainly infected by Candida albicans. Mycosis has a long course of disease and a hig...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/72A61K9/20A61K9/16A61K9/06A61K9/12A61P31/10
Inventor 徐超群袁志翔张磊舒光明杨薇余悦胡竟一李东晓
Owner 四川梓橦宫药业股份有限公司
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